Two cases of tick‐borne transmitted tularemia on Southern Zealand, Denmark

Morten Bahrt Haulrig*, Gustav Mathiasen, Rikke Maria Nielsen, Charles Boy Kromann, Karen Angeliki Krogfelt, Lothar Wiese

*Corresponding author

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Francisella tularensis is a zoonotic bacterium which causes the infection tularemia. It colonizes invertebrates and vertebrates, counting wildlife animals and rodents. Humans can become infected through several pathways including contaminated food, water, and handling animals and due to bites from vectors. Ticks are known to cause tularemia in humans, though their role as a disease transferring vector is not well understood. We describe two case reports of tularemia transferred by ticks on Southern Zealand, Denmark. Case 1: A 49-year-old woman presented with lymphadenopathy and an unhealed sifting wound after a tick bite. Serology tests for F. tularensis were initially negative but turned positive five weeks after symptom onset, when abscess drainage was performed. Gentamicin and ciprofloxacin treatment improved the patient's clinical condition, and she completely recovered. Case 2: A 74-year-old man presented with malaise, fever, and an abdominal ulcer allegedly caused after a vector bite. CRP and leukocytes were increased, while serology tests for F. tularensis were negative. Doxycycline treatment improved the patient's clinical condition, and he completely recovered. Three weeks after symptom onset, renewed serology tests for F. tularensis were positive.
Original languageEnglish
JournalAPMIS - Journal of Pathology, Microbiology and Immunology
Volume128
Issue number1
Pages (from-to)61-64
Number of pages4
ISSN0903-4641
DOIs
Publication statusPublished - 2020

Bibliographical note

Important note from the Publisher regarding the attached version of the article: "This is the peer reviewed version of the following article: Haulrig, MB, Mathiasen, G, Nielsen, RM, Kromann, CB, Krogfelt, KA, Wiese, L. Two cases of tick‐borne transmitted tularemia on Southern Zealand, Denmark. APMIS 2020; 128: 61– 64. , which has been published in final form at https://doi.org/10.1111/apm.13008. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions."

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