The development of subjective quality of life over the first 2 years in first-episode psychosis

Ingrid Melle, Jan Ivar Røssberg, Inge Joa, Svein Friis, Ulrik Haahr, Jan-Olav Johannessen, Tor Ketil Larsen, Stein Opjordsmoen, Bjørn Rishovd Rund, Erik Simonsen, Per Vaglum, Thomas H. McGlashan

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    The main aim of this study was to examine changes in subjective quality of life (general s-QoL) in patients with first-episode psychosis from baseline to 2 years follow-up. A total of 201 of 252 patients had full quality of life assessment at both baseline and at 2 years. Repeated measure analyses of variance were done to evaluate the development over time, and multiple linear regression analyses to evaluate predictors of change. These patients with a first-episode psychosis showed a significant improvement in general s-QoL during the first 2 years of treatment. Improvements in general s-QoL were associated with increase in excitative symptoms and with improvements in depressive symptoms, global functioning, level of daily activities, level of social activities, and perceived general health.
    Original languageEnglish
    JournalJournal of Nervous and Mental Disease
    Issue number12
    Pages (from-to)864-869
    Number of pages6
    Publication statusPublished - 2010

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