Tautomerism and biological activity of beta-diketoner, triketoner, beta-ketoesters and beta-ketoamides. A mini review

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The review deals with β-diketones, β-ketoester, β-ketoamides, triketones, their
tautomerism and biological activity. In addition, it covers briefly methods to detect
tautomerism in particular NMR and deuterium isotope effects on chemical shifts,
both primary and secondary. A number of typical systems are treated such as: usnic
acid, tetracyclines, piroxicam, curcurmines, humulones, acyltetramic acids and
quinolone 3-esters.
Original languageEnglish
JournalWiadomosci Chemiczne
Issue number7-8
Pages (from-to)428-446
Number of pages19
Publication statusPublished - 3 Aug 2017


  • Tautomerism
  • biological activity
  • beta-diketones
  • triketones
  • beta-ketoesters

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