Synthesis of macrocyclic lactams and lactones via ring-closing olefin metathesis

W. P. D. Goldring; A. S. Hodder; L. Weiler

doi:10.1016/S0040-4039(98)00966-6

Synthesis of macrocyclic lactams and lactones via ring-closing olefin metathesis

W. P. D. Goldring, A. S. Hodder, L. Weiler

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Lactones and lactams 4–6 were synthesized from a series of acyclic dienes 1–3 via ring-closing olefin metathesis, as shown in equation 1. The geometry of the resulting double bond was determined, and the EIZ ratios compared to values from molecular mechanics calculations.

Original language	English
Journal	Tetrahedron Letters
Volume	39
Issue number	28
Pages (from-to)	4955-4958
Number of pages	4
ISSN	0040-4039
DOIs	https://doi.org/10.1016/S0040-4039(98)00966-6
Publication status	Published - 1998
Externally published	Yes

Link to document

10.1016/S0040-4039(98)00966-6

Cite this

@article{63b1e760166a4baa9b8e50485058f478,

title = "Synthesis of macrocyclic lactams and lactones via ring-closing olefin metathesis",

abstract = "Lactones and lactams 4–6 were synthesized from a series of acyclic dienes 1–3 via ring-closing olefin metathesis, as shown in equation 1. The geometry of the resulting double bond was determined, and the EIZ ratios compared to values from molecular mechanics calculations.",

author = "Goldring, {W. P. D.} and Hodder, {A. S.} and L. Weiler",

year = "1998",

doi = "10.1016/S0040-4039(98)00966-6",

language = "English",

volume = "39",

pages = "4955--4958",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Pergamon Press",

number = "28",

}

TY - JOUR

T1 - Synthesis of macrocyclic lactams and lactones via ring-closing olefin metathesis

AU - Goldring, W. P. D.

AU - Hodder, A. S.

AU - Weiler, L.

PY - 1998

Y1 - 1998

N2 - Lactones and lactams 4–6 were synthesized from a series of acyclic dienes 1–3 via ring-closing olefin metathesis, as shown in equation 1. The geometry of the resulting double bond was determined, and the EIZ ratios compared to values from molecular mechanics calculations.

AB - Lactones and lactams 4–6 were synthesized from a series of acyclic dienes 1–3 via ring-closing olefin metathesis, as shown in equation 1. The geometry of the resulting double bond was determined, and the EIZ ratios compared to values from molecular mechanics calculations.

U2 - 10.1016/S0040-4039(98)00966-6

DO - 10.1016/S0040-4039(98)00966-6

M3 - Journal article

VL - 39

SP - 4955

EP - 4958

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 28

ER -