Structural studies of chemical constituents of Thithonia Tagetiflora Desv (Asteraceae)

Vinh Ngoc Huynh; Thu Nguyen Thi Hoai; Kim Phi Phung Nguyen; Poul Erik Hansen

doi:10.1002/mrc.3963

Structural studies of chemical constituents of Thithonia Tagetiflora Desv (Asteraceae)

Vinh Ngoc Huynh, Thu Nguyen Thi Hoai, Kim Phi Phung Nguyen, Poul Erik Hansen

Chemistry

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Tithonia tagetiflora Desv. (Asteraceae) is a widespread plant in Vietnam, and the species of Tithonia are known as plants containing many biologically active compounds. However, T. tagetiflora's chemical composition remains mostly unknown. Therefore, we now report the structural elucidation of two new sesquiterpene lactones, 8-angeloyloxy-2,14-epoxygermacra-4,10(1),11(13)-trien-6,12-olide (1) and 6-angeloyloxy-1-hydroxy-3,4-epoxygermacra-9,11(13)-dien-8,12-olide (2), together with three known compounds, including two norisoprenoids, (6S,9S)-vomifoliol or (6R,9R)-vomifoliol (3) and (6S,9S)-roseoside (4), and one glutinane type triterpene, epi-glutinol (5), from the leaves of T. tagetiflora. Their structures are established by 1D and 2D NMR spectroscopy, as well as ESI-MS analysis and comparison with literature data

Original language	English
Journal	Magnetic Resonance in Chemistry
Volume	51
Issue number	7
Pages (from-to)	439-443
Number of pages	5
ISSN	0749-1581
DOIs	https://doi.org/10.1002/mrc.3963
Publication status	Published - 2013

Link to document

10.1002/mrc.3963

Cite this

@article{873948227c7c457d871b6b44e3c20f96,

title = "Structural studies of chemical constituents of Thithonia Tagetiflora Desv (Asteraceae)",

abstract = "Tithonia tagetiflora Desv. (Asteraceae) is a widespread plant in Vietnam, and the species of Tithonia are known as plants containing many biologically active compounds. However, T. tagetiflora's chemical composition remains mostly unknown. Therefore, we now report the structural elucidation of two new sesquiterpene lactones, 8-angeloyloxy-2,14-epoxygermacra-4,10(1),11(13)-trien-6,12-olide (1) and 6-angeloyloxy-1-hydroxy-3,4-epoxygermacra-9,11(13)-dien-8,12-olide (2), together with three known compounds, including two norisoprenoids, (6S,9S)-vomifoliol or (6R,9R)-vomifoliol (3) and (6S,9S)-roseoside (4), and one glutinane type triterpene, epi-glutinol (5), from the leaves of T. tagetiflora. Their structures are established by 1D and 2D NMR spectroscopy, as well as ESI-MS analysis and comparison with literature data",

keywords = "NMR, norisoprenoid, sesquiterpene lactone, asteraceae",

author = "{Ngoc Huynh}, Vinh and {Nguyen Thi Hoai}, Thu and {Phi Phung Nguyen}, Kim and Hansen, {Poul Erik}",

year = "2013",

doi = "10.1002/mrc.3963",

language = "English",

volume = "51",

pages = "439--443",

journal = "Magnetic Resonance in Chemistry",

issn = "0749-1581",

publisher = "JohnWiley & Sons Ltd.",

number = "7",

}

TY - JOUR

T1 - Structural studies of chemical constituents of Thithonia Tagetiflora Desv (Asteraceae)

AU - Ngoc Huynh, Vinh

AU - Nguyen Thi Hoai, Thu

AU - Phi Phung Nguyen, Kim

AU - Hansen, Poul Erik

PY - 2013

Y1 - 2013

N2 - Tithonia tagetiflora Desv. (Asteraceae) is a widespread plant in Vietnam, and the species of Tithonia are known as plants containing many biologically active compounds. However, T. tagetiflora's chemical composition remains mostly unknown. Therefore, we now report the structural elucidation of two new sesquiterpene lactones, 8-angeloyloxy-2,14-epoxygermacra-4,10(1),11(13)-trien-6,12-olide (1) and 6-angeloyloxy-1-hydroxy-3,4-epoxygermacra-9,11(13)-dien-8,12-olide (2), together with three known compounds, including two norisoprenoids, (6S,9S)-vomifoliol or (6R,9R)-vomifoliol (3) and (6S,9S)-roseoside (4), and one glutinane type triterpene, epi-glutinol (5), from the leaves of T. tagetiflora. Their structures are established by 1D and 2D NMR spectroscopy, as well as ESI-MS analysis and comparison with literature data

AB - Tithonia tagetiflora Desv. (Asteraceae) is a widespread plant in Vietnam, and the species of Tithonia are known as plants containing many biologically active compounds. However, T. tagetiflora's chemical composition remains mostly unknown. Therefore, we now report the structural elucidation of two new sesquiterpene lactones, 8-angeloyloxy-2,14-epoxygermacra-4,10(1),11(13)-trien-6,12-olide (1) and 6-angeloyloxy-1-hydroxy-3,4-epoxygermacra-9,11(13)-dien-8,12-olide (2), together with three known compounds, including two norisoprenoids, (6S,9S)-vomifoliol or (6R,9R)-vomifoliol (3) and (6S,9S)-roseoside (4), and one glutinane type triterpene, epi-glutinol (5), from the leaves of T. tagetiflora. Their structures are established by 1D and 2D NMR spectroscopy, as well as ESI-MS analysis and comparison with literature data

KW - NMR

KW - norisoprenoid

KW - sesquiterpene lactone

KW - asteraceae

U2 - 10.1002/mrc.3963

DO - 10.1002/mrc.3963

M3 - Journal article

SN - 0749-1581

VL - 51

SP - 439

EP - 443

JO - Magnetic Resonance in Chemistry

JF - Magnetic Resonance in Chemistry

IS - 7

ER -