Novel culturing platform for brain slices and neuronal cells

Winnie Edith Svendsen, Fatima AlZahraa Alatraktchi, Tanya Bakmand, Helle Waagepetersen, Maria Dimaki

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Abstract

In this paper we demonstrate a novel culturing system for brain slices and neuronal cells, which can control the concentration of nutrients and the waste removal from the culture by adjusting the fluid flow within the device. The entire system can be placed in an incubator. The system has been tested successfully with brain slices and PC12 cells. The culture substrate can be modified using metal electrodes and/or nanostructures for conducting electrical measurements while culturing and for better mimicking the in vivo conditions.
Original languageEnglish
Title of host publication37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Number of pages4
PublisherIEEE
Publication date2015
Pages346-349
ISBN (Electronic)978-1-4244-9271-8
DOIs
Publication statusPublished - 2015
Externally publishedYes

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