Molecular dynamics simulations of valveless pumping in a closed microfluidic tube-system

J.S. Hansen, Johnny T. Ottesen, A. Lemarchard

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    Abstract

    In this paper we study the flow which is generated by a valveless pumping mechanism in a closed tube-system consistent of two tubes with different radii. This remarkable system has been investigated by Ottesen [J. T. Ottesen, J. Math. Biol. 46(2003) 309-332] on a macroscopic level and we find that the results from the microscopic molecular dynamics simulations qualitatively agree with the macroscopic results. Especially, is it shown that the direction of the flow is changed by simply changing the frequency of the pumping device. We also study the local flow generated in the system and find that the velocity profiles away from the pumping area can be well fitted to an analytical solution of the Navier-Stokes equation.
    Original languageEnglish
    JournalMolecular Simulation
    Volume31
    Issue number14-15
    Pages (from-to)963 - 969
    Number of pages6
    ISSN0892-7022
    Publication statusPublished - 2005

    Keywords

    • Valveless pumping
    • Molecular dynamics
    • Flow direction
    • Moment current
    • Pulsating flow
    • Womersley parameter

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