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Modeling repeats in DNA using extended probabilistic regular expressions

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Abstract

Regular expressions is a familiar and widely used formalism which is integrated in many modern programming languages. Contemporary versions of regular expressions are typically extended variants whose expressive power goes beyond regular languages. Extended regular expressions are inherently non-deterministic and require procedural control such as backtracking. We propose a probabilistic version of extended regular expressions, where the affinity for strings and matches can be learned from examples. The procedural control semantics are replaced by a probabilistic semantics, where the possible matches are ranked by their probability and the most probable match is the one returned. In the present paper, we show how probabilistic extended regular expressions can be used to model repeats in DNA. To deal with cases where the expressive power of probabilistic extended regular expressions is insufficient, we extend the syntax to integrate external functions, which may be deterministic or probabilistic
Original languageEnglish
Title of host publicationBiology, Computation and Linguistics : Proceedings of 1st International Work-Conference on Linguistics, Biology and Computer Science: Interplays
EditorsGemma Bel-Enguix, Veronica Dahl, M. Dolores Jimenez-Lopez
Volume228
PublisherIOS Press
Publication date2011
Pages55-70
ISBN (Print)978-1-60750-761-1
ISBN (Electronic)978-1-60750-762-8
DOIs
Publication statusPublished - 2011
Event1st International Work-Conference on Linguistics, Biology and Computer Science: Interplays - Tarragona, Spain
Duration: 14 Mar 201118 Mar 2011
http://interplaysconference.wordpress.com/

Conference

Conference1st International Work-Conference on Linguistics, Biology and Computer Science
Country/TerritorySpain
CityTarragona
Period14/03/201118/03/2011
Internet address

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