Abstract
Nosocomial infections caused by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are a major concern worldwide. There is an urgent need to identify bacterial factors promoting survival and persistence of these organisms in the nosocomial environment. Here, we describe the presence of a gene cluster, containing the Clp ATPase ClpK, within a collection of Danish ESBL-producing E. coli isolates. The cluster conferred thermoprotection upon the isolates, and thus might facilitate survival on medical devices exposed to semi-high temperatures in a hospital setting.
Original language | English |
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Journal | Research in Microbiology |
Volume | 167 |
Issue number | 5 |
Pages (from-to) | 345-349 |
Number of pages | 5 |
ISSN | 0923-2508 |
DOIs | |
Publication status | Published - 2016 |
Externally published | Yes |
Keywords
- ESBL-producing Escherichia coli
- Heat resistance
- Nosocomial infection