Efficient Friedel-Crafts benzoylation of aniline derivatives with 4-fluorobenzoyl chloride using copper triflate in the synthesis of aminobenzophenones

Phuong Hoang Tran, Huy Quang Phung, Poul Erik Hansen, Hai Ngoc Tran, Thach Ngoc Le

Research output: Contribution to journalJournal articleResearchpeer-review


An efficient pathway for the synthesis of the aminobenzophenone
derivatives via Friedel–Crafts benzoylation using copper triflate as
catalyst is proposed. New derivatives are synthesized. The copper
triflate could be easily recovered and reused without loss of catalytic
activity. Both the use of ionic liquids and microwave heating turned
out to be fruitful.
Original languageEnglish
JournalSynthetic Communications
Issue number10
Publication statusPublished - 2016

Bibliographical note

Imortant note from the Publisher regarding the attached document:
“This is an Accepted Manuscript of an article published by Taylor & Francis in Synthetic Communication on 03 Jun 2016, available online: http://www.tandfonline.com/10.1080/00397911.2016.1148164.”

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