Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome

George D Vavougios; Marianthi Breza; Sotirios Zarogiannis; Karen A Krogfelt; Sygkliti-Henrietta Pelidou; Triantafyllos Doskas

Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome

George D Vavougios, Marianthi Breza, Sotirios Zarogiannis, Karen A Krogfelt, Sygkliti-Henrietta Pelidou, Triantafyllos Doskas

Research output: Contribution to conference › Poster › Research › peer-review

Abstract

It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.

Original language	English
Publication date	2020
Publication status	Published - 2020
Event	6th Congress of the European Academy of Neurology (Online) - Online, Paris, France Duration: 23 May 2020 → 26 May 2020 Conference number: 6 https://www.ean.org/congress-2020

Conference

Conference	6th Congress of the European Academy of Neurology (Online)
Number	6
Location	Online
Country/Territory	France
City	Paris
Period	23/05/2020 → 26/05/2020
Internet address	https://www.ean.org/congress-2020

Link to document

https://www.researchgate.net/publication/341868049_Comparative_transcriptomics_of_multiple_sclerosis_vs_Viral_infections_common_roles_for_nuclear_transport_neuroactive_peptide_signalling_and_the_spliceosome

Cite this

Vavougios, G. D., Breza, M., Zarogiannis, S., Krogfelt, K. A., Pelidou, S.-H., & Doskas, T. (2020). Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome. Poster session presented at 6th Congress of the European Academy of Neurology (Online), Paris, France. https://www.researchgate.net/publication/341868049_Comparative_transcriptomics_of_multiple_sclerosis_vs_Viral_infections_common_roles_for_nuclear_transport_neuroactive_peptide_signalling_and_the_spliceosome

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title = "Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome",

abstract = "It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.",

author = "Vavougios, {George D} and Marianthi Breza and Sotirios Zarogiannis and Krogfelt, {Karen A} and Sygkliti-Henrietta Pelidou and Triantafyllos Doskas",

year = "2020",

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Vavougios, GD, Breza, M, Zarogiannis, S, Krogfelt, KA, Pelidou, S-H & Doskas, T 2020, 'Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome', 6th Congress of the European Academy of Neurology (Online), Paris, France, 23/05/2020 - 26/05/2020. <https://www.researchgate.net/publication/341868049_Comparative_transcriptomics_of_multiple_sclerosis_vs_Viral_infections_common_roles_for_nuclear_transport_neuroactive_peptide_signalling_and_the_spliceosome>

Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome. / Vavougios, George D; Breza, Marianthi; Zarogiannis, Sotirios et al.
2020. Poster session presented at 6th Congress of the European Academy of Neurology (Online), Paris, France.

Research output: Contribution to conference › Poster › Research › peer-review

TY - CONF

T1 - Comparative transcriptomics of multiple sclerosis vs. Viral infections

T2 - 6th Congress of the European Academy of Neurology (Online)

AU - Vavougios, George D

AU - Breza, Marianthi

AU - Zarogiannis, Sotirios

AU - Krogfelt, Karen A

AU - Pelidou, Sygkliti-Henrietta

AU - Doskas, Triantafyllos

N1 - Conference code: 6

PY - 2020

Y1 - 2020

N2 - It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.

AB - It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.

M3 - Poster

Y2 - 23 May 2020 through 26 May 2020

ER -