Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome

George D Vavougios, Marianthi Breza, Sotirios Zarogiannis, Karen A Krogfelt, Henrietta--Sygkliti Pelidou, Triantafyllos Doskas

Research output: Contribution to conferencePosterResearchpeer-review

Abstract

It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.
Original languageEnglish
Publication date2020
Publication statusPublished - 2020
Event6th Congress of the European Academy of Neurology - Online, Paris, France
Duration: 23 May 202026 May 2020
https://www.ean.org/congress-2020

Conference

Conference6th Congress of the European Academy of Neurology
LocationOnline
CountryFrance
CityParis
Period23/05/202026/05/2020
Internet address

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