Research output per year
Research output per year
Personal profile
Research
My main research areas are developmental biology (embryology) and bioimaging.
I focus on the formation of endocrine organs during embryonic development. I am especially fascinated by the general biological question of:
How the dynamic behavior of individual cells results in the final shape of the organ and guides cell differentiation
Currently my group focuses on neuro-organ crosstalk, i.e. how innervation of endocrine organs influence their development and function.
In order to address these questions my group studies the embryonic pancreas and thyroid. Our research models include transgenic mice and 3D growth of various cell lines. We employ novel high-resolution live imaging methods, and develop new deep-learning based methods for quantitative analysis of 4D bio-imaging data together with collaborators.
Scientific keywords:
Developmental biology
Molecular Biology
Endocrinology
Pancreas
beta cells
Thyroid
Organogenesis
Tubulogenesis
Cell Signaling
Cell differentiation
Bioimaging
Microscopy
Live imaging
Transgenic mouse models (fluorescent reporters)
Machine learning based image analysis
Contact me regarding expertize in:
Embryo/foetal development
Bioimaging
Stem cells and stem cell therapy
Pancreatic diseases such as diabetes
Digital learning tools
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biology, PhD , University of Copenhagen
Award Date: 19 Jun 2008
External positions
Visiting Researcher, University of Copenhagen
1 May 2019 → 30 Dec 2022
Keywords
- Health, Medicine
- Endocrinology
- Biology, Biotechnology
- Developmental biology
- Organogenesis
- Cell signalling
- Stem cells
- Confocal microscopy
- Bioimaging
- Image analysis
- Education, Learning, Training
- Digital learning tools
Publication network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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DNAJB6 is expressed in neurons and oligodendrocytes of the human brain
Hentze, J., Folke, J., Aznar, S., Nyeng, P., Brudek, T. & Hansen, C., Dec 2024, In: GLIA. 72, 12, p. 2313-2326 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
File -
Innervation of the pancreas in development and disease
Agerskov, R. H. & Nyeng, P., 15 Jan 2024, In: Development. 151, 2, dev202254.Research output: Contribution to journal › Review › peer-review
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The Effect of Different Time Scales in Cell and Developmental Biology as Recorded by Microscopy
Nyeng, P., 2024, Multiplicity of Time Scales in Complex Systems: Challenges for Sciences and Communication I. Booß-Bavnbek, B., Hesselbjerg Christensen, J., Richardson, K. & Vallès Codina, O. (eds.). Springer, p. 205–213 (Mathematics Online First Collections).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Real time quantification of apical polarity protein reveals novel dynamic processes in luminal network establishment and remodeling in the pancreas
Laura Jackson, A., Heilmann, S., Ebied, C., Krivokapic, J. M., Herrer, J. A. R., Semb, H. & Nyeng, P., 11 Aug 2023, bioRxiv.Research output: Working paper › Preprint
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Quantifying Topology In Pancreatic Tubular Networks From Live Imaging 3D Microscopy
Arnavaz, K., Krause, O., Zepf, K., Bærentzen, J. A., Krivokapic, J. M., Heilmann, S., Nyeng, P. & Feragen, A., Jul 2022, In: The journal of Machine Learning for Biomedical Imaging (MELBA). 2022, June, p. 1-24Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile
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Investigating the role of neurotransmitters in pancreatic development and islet cell function by simultaneous and continuous high-sensitivity neurotransmitter sensing and 4D bioimaging
Agerskov, R. (Project participant), Nyeng, P. (Supervisor), Lund, T. (Co-supervisor), Alatraktchi, F. A. (Co-supervisor) & Dalgaard, L. T. (Co-supervisor)
15/02/2024 → 14/02/2027
Project: Research
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PAC: Pancreatic crosstalk: Does innervation guide pancreatic organogenesis and beta cell formation?
Nyeng, P. (Project participant), Feragen, A. (Project participant) & Agerskov, R. (Project participant)
01/09/2022 → 01/07/2024
Project: Research
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Establishment and remodeling of mouse pancreatic tubes revealed by live imaging of apical polarity
Nyeng, P. (Project participant), Heilmann, S. (Project participant), Laura Jackson, A. (Project participant) & Semb, H. (Project participant)
01/12/2019 → 31/07/2023
Project: Research
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Quantifying the topological events connecting tubulogenesis and beta-cell differentiation
Feragen, A. (Project participant), Nyeng, P. (Project participant), Semb, H. (Project participant), Arnavaz, K. (Project participant), Krivokapic, J. M. (Project participant) & Krause, O. (Project participant)
01/08/2019 → 30/11/2021
Project: Research
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Biological network formation and cell fate allocation in the developing pancreas
Nyeng, P. (Speaker)
9 Apr 2024Activity: Talk or presentation › Lecture and oral contribution
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Image analysis from a microscopist’s viewpoint
Nyeng, P. (Speaker)
12 May 2023Activity: Talk or presentation › Lecture and oral contribution
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Multicellular crosstalk: Uncovering the interplay between pancreatic cell lineages by 3D live cell imaging and deep-learning assisted analysis
Nyeng, P. (Speaker)
10 Feb 2023Activity: Talk or presentation › Lecture and oral contribution
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Multicellular crosstalk: Uncovering the interplay between pancreatic cell lineages by 3D live cell imaging and deep-learning assisted analysis
Nyeng, P. (Speaker)
22 Oct 2022Activity: Talk or presentation › Lecture and oral contribution
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Is seeing really believing? Emergence of different processes in measurements of living tissue under different time scales
Nyeng, P. (Speaker)
23 Aug 2022 → 24 Aug 2022Activity: Talk or presentation › Lecture and oral contribution
Press/Media
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For biolog er tværfagligheden en stige over den mur, som hendes felt har ramt
09/11/2024
1 item of Media coverage
Press/Media: Press / Media
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Lektor modtager fire mio. kr. til tværfaglig forskning i fosterudviklingens biologiske netværk
15/10/2024
1 item of Media coverage
Press/Media: Press / Media
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The Semb group - from basic research to translational applications
10/08/2020
1 item of Media coverage
Press/Media: Press / Media
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New study sorts out how the destiny of cells is determined
12/04/2019
1 item of Media coverage
Press/Media: Press / Media
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Datasets
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Pancreas_sample_images
Heilmann, S. (Creator) & Nyeng, P. (Contributor), Mendeley Data, 11 Aug 2021
DOI: 10.17632/nr9cyyk265.1, https://data.mendeley.com/datasets/nr9cyyk265
Dataset