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Personal profile

Research

My main research interest is the formation of the 3D architecture of internal organs during embryonic development. I am especially fascinated by the general biological question of:

How the dynamic behavior of individual cells results in the final shape of the organ and guides cell differentiation

Currently my group also focuses on the related question:

How cell differentiation and cellular dynamics are coordinated between different cell lineages (epithelial, endothelial and neuronal) during organogenesis

In order to address these questions my group studies the embryonic pancreas. Our research models include transgenic mice and 3D growth of various cell lines. We employ novel high-resolution live imaging methods, and am currently developing new deep-learning based methods for quantitative analysis of 4D bio-imaging data together with my collaborators.

Keywords:

Developmental biology

Molecular Biology

Pancreas

Organogenesis

Tubulogenesis

Cell Signaling

Cell differentiation

 

Methods:

Microscopy

Confocal microscopy

Live imaging

Transgenic mouse models (fluorescent reporters)

BAC recombineering

Immunofluorescence

Histology

Protein and mRNA expression

Machine learning based image analysis

 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education
  • SDG 15 - Life on Land

Education/Academic qualification

Biology, PhD , University of Copenhagen, Faculty of Health and Medical Sciences

Award Date: 19 Jun 2008

External positions

Visiting Researcher, Danstem, University of Copenhagen

1 May 2019 → …

Keywords

  • Biology, Biotechnology
  • Health, Medicine

Publication network

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