Research output per year
Research output per year
MSc & PhD
Universitetsvej 1, 28A.2
DK-4000 Roskilde
Denmark
My research aims to find new ways to prevent and cure important bacterial infections. To this end, I study the molecular mechanisms of host-pathogen interactions and host-adaptation of bacterial infections to identify novel virulence mechanism and develop these into suitable antimicrobial targets. I am particularly interested in elucidating the molecular mechanisms of the link between pathogen in vivo metabolism and virulence, and how metabolic status affects disease progression, with a potential for identifying novel pathogen-specific targets for treatment of bacterial infections. To this end, I am employing the human pathogen Salmonella Typhimurium as a model for both intestinal and systemic infections of a mouse model. In relation to this, I have in recent studies, characterized the essential metabolic capacity of Salmonella for successful infections and identified several metabolic pathways that are essential for virulence of Salmonella. In a current study, I have isolated a strain of Salmonella that has adapted to the systemic environment during persistent infections. Using Whole Genome Sequencing, I have identified novel metabolic enzymes that are essential for chronic Salmonella infections.
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Working paper › Preprint
Research output: Contribution to journal › Journal article › Communication
Research output: Contribution to journal › Journal article › Research › peer-review
Jelsbak, L., Iversen, S. & Andersen, P. S.
01/02/2020 → 31/01/2023
Project: Research
Jelsbak, L., Goldring, W. & Lallement, C.
01/05/2020 → 30/04/2022
Project: Research
Jelsbak, L., Andreasen, M. R., Schønning, K. & Hansen, K. H.
04/12/2017 → 30/06/2022
Project: Research
01/11/2015 → 31/10/2016
Project: Research
19/12/2019
1 item of Media coverage
Press/Media: Press / Media