Photo of Anders Malmendal

Anders Malmendal

Associate Professor, PhD

  • Universitetsvej 1, 28C.1

    DK-4000 Roskilde

    Denmark

19972019
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Personal profile

Research

My specialty is to find simple patterns to help us understand complex biological systems. My most important tools are NMR spectroscopy, which provides information on almost every atom in a molecule or a mixture of molecules, and multivariate analysis, which is needed to make sense of this complex information. 

I have a unique combination of experiences with different types of biological NMR and other measurements: Biophysical chemistryand structural biology, including structural and dynamic characterization of proteins and their interactions. A special interest is to use NMR and other biophysical methods to understand protein aggregation, in order to get increased understanding of neurodegenerative disorders. Metabolomics, a method to characterize the complex (bio-) chemical trajectory of any biological or other process. Special interests here areDrosophilamodels for genetic and environmental factors and for human disease and metabolite responses for process control in biotechnology. I am very interested in how NMR metabolomics can be used now and in the future.

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Research Output 1997 2019

  • 68 Journal article

A method of predicting the in vitro fibril formation propensity of Abeta40 mutants based on their inclusion body levels in E. coli

Sanagavarapu, K., Nüske, E., Nasir, I., Meisl, G., Immink, J. N., Sormanni, P., Vendruscolo, M., Knowles, T. P. J., Malmendal, A., Cabaleiro-Lago, C. & Linse, S., 2019, In : Scientific Reports. 9, 1, 3680.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

In-hospital metabolite changes in infective endocarditis: a longitudinal 1H NMR-based study

Klein, C. F., Holle, S. L. K., Andersen, M. H., Pedersen, A., Bundgaard, H., Iversen, K. K. & Malmendal, A., 2019, In : European Journal of Clinical Microbiology & Infectious Diseases. 2019, 38, p. 1553-1560

Research output: Contribution to journalJournal articleResearchpeer-review

pKa Determination of a Histidine Residue in a Short Peptide Using Raman Spectroscopy

Pogostin, B. H., Malmendal, A., Londergan, C. H. & Åkerfeldt, K. S., 2019, In : Molecules. 24, 3, E405.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Revealing Well-Defined Soluble States during Amyloid Fibril Formation by Multilinear Analysis of NMR Diffusion Data

Jensen, K. S., Linse, S., Nilsson, M., Akke, M. & Malmendal, A., 13 Nov 2019, In : Journal of the American Chemical Society. 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Metabolic and functional phenotypic profiling of Drosophila melanogaster reveals reduced sex differentiation under stressful environmental conditions

Ørsted, M., Malmendal, A., Muñoz, J. & Kristensen, T. N., 2018, In : Biological Journal of the Linnean Society. 123, 1

Research output: Contribution to journalJournal articleResearchpeer-review