Description
Our inner organs are communities of several cell types, each with their own origin and specialized function. How these cells assemble into a functional organ in the developing embryo is a fundamental question in developmental biology. Our vision is to move beyond the classical studies of separate cell lineages by studying co-development of cell lineages in real time. The pancreas produces blood glucose regulating hormones and enzymes needed for digestion, and is a highly vascularized and innervated organ, making it an interesting case for a co-development study. Employing a combination of mouse genetics, 3D live imaging of explanted whole organs, and deep-learning assisted analysis we have identified spatial and temporal correlations and dependencies between diverse cell lineages found in the pancreas. In this talk I will present unpublished data from a large-scale imaging project where tubulogenesis of duct cells and differentiation of beta cells were studied in parallel and analyzed by deep-learning algorithms.| Period | 22 Oct 2022 |
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| Event title | Emerging Concepts in Cell & Developmental Biology Conference |
| Event type | Conference |
| Location | Aarhus, DenmarkShow on map |
| Degree of Recognition | International |