Titration by datA Locus in the Bacterial Choromosome

Yuan Zhang, Hongbo Liu, Xiaofang Ma & Jing Wang

Studenteropgave: Semesterprojekt


Bacterial chromosome replication initiates by binding of DnaA protein to the origin. DnaA protein is a sequence-specific DNA binding protein, which binds to eight DnaA boxes in the origin. There are also DnaA boxes on the datA region, which can influence the replication initiation through different binding affinity with DnaA protein. We analyzed the binding activity and sequence features of DnaA boxes in datA by melecular titration assay and bioinfomatics study.

UddannelserMolekylærbiologi, (Bachelor/kandidatuddannelse) Bachelor el. kandidatEngelsk, (Bachelor/kandidatuddannelse) Bachelor el. kandidat
Udgivelsesdato29 jun. 2007
VejledereTove Atlung


  • datA
  • DnaA