Steroidøstrogeners skadelige virkning på fisk: Steroid estrogens harmful effect on fish

Cecilie Felicia Hansen, Kenneth Nielsen, Sophia Alberte Fisker Rasmussen, Anders Meidahl Münsberg & Julie Lundbak Kofod

Studenteropgave: Semesterprojekt


Based on a literature study we will describe how steroid estrogens affect fish. Experiments show that male fish become feminized when exposed to the synthetic hormone EE2 (17α-ethinylestradiol). EE2 is a chemical compound in the recipe of anti-conceptive pills; it is excreted in the urine by the women taking the pills, and eventually ends up in the sewage wastewater. While in the initial phase of the sewage treatment plant, the compound is considered inactive, but when passing through the processes of the sewage treatment plant it gets activated and finally it is present in the aquatic environment. Measured concentrations around Denmark show values exceeding the LOEL (Lowest Observable Effect Level) and values under the LOEL. Despite some concentrations exceed the LOEL, a common consensus is still lacking whether EE2 have any consequences for the Danish aquatic environment. The discharge of the synthetic hormone EE2 has not been reported to affect the Danish water environment. Still there has been observed feminized fish in the fish's habitat in Denmark. Another source that could cause the feminization is the natural female hormone E2 that increases under pregnancy. The manure from pregnant sows has a large content of the hormone and it gets in the water when it is spread on surrounding fields. Concentrations in water measured near the field shows that the concentrations mainly stay under the LOEL. It is reported in the scientific literature that the synthetic hormone (EE2) has potential to bioaccumulate in for example fish tissues. This means that EE2 possibly can end up in the human body if a fish, containing the hormone, is consumed.

UddannelserBasis - Naturvidenskabelig Bacheloruddannelse, (Bachelor uddannelse) Basis
Udgivelsesdato18 jan. 2012
VejledereBenni Winding Hansen


  • ålekvabbe
  • zebrafisk
  • østron
  • e1
  • e2
  • estrone
  • vitellogenin
  • hormonforstyrrende stoffer
  • ee2
  • ethinyløstradiol
  • steroidøstrogener
  • p-piller
  • endokrine forstyrrere
  • østradiol
  • 17β-estradiol
  • bioakkumulation
  • 17α-ethinylestradiol