Staphylococcus Aureus Host-Interactions

Gleb Dudnik

Studenteropgave: Semesterprojekt


S. aureus is a rising health issue due to it's high pathogenicity, mortality and drug resistance. Due to the failed antibiotic treatment of multidrug resistant S. aureus like MRSA it is important to look for alternative therapies. Human innate immunity might be one such therapy. It will be shown here that an innate immunity induction via either MyD88-dependent PRRs or via an HIF-1 activation could be the answer, was it not for S. aureus ability to destroy neutrophiles and macrophages. This makes the innate immunity activation therapy a game of chance, should this therapy used alone. The innate immunity therapy might be promising though when used together with vaccination. And an IL-1 receptor, the activator of B cells, might be just an example of that. 1

UddannelserMedicinalbiologi, (Bachelor/kandidatuddannelse) Bachelor el. kandidat
Udgivelsesdato28 jan. 2015
VejledereLotte Jelsbak


  • Staphylococcus aureus
  • innate immune system