Size dependence on pressure and concentration of extruded DMPC vesicles

Mikkel Sakse Bennetsen, Daniel Olesen Fejerskov & Nathan Hugh Barr

Studenteropgave: Kandidatprojekt

Abstrakt

In this project, the properties of unilamellar vesicles created by the method of extrusion from DMPC is investigated. The work is based largely on the model presented by Frisken and Patty in \cite{Frisken2003}. By extruding DMPC at several different pressures and at several different concentrations, we test the generalisability of the model by both changing the lipid used, as the authors use POPC, and by investigating whether their model takes into account the significance of the concentration used. The results are obtained by the method of dynamic light scattering. We find that their model is applicable to DMPC, but that it is only applicable within a low concentration regime. We postulate that some factor changes in the fluid. We further postulate that this change has to do with the viscosity or the surface tension of the liquid as the concentration changes.

UddannelserFysik, (Bachelor/kandidatuddannelse) Kandidat
SprogEngelsk
Udgivelsesdato2 jan. 2018
Antal sider67
VejledereDorthe Posselt

Emneord

  • DLS
  • Dynamic light scattering
  • DMPC
  • Vesicles
  • Extrusion
  • Quick Math
  • Scattering
  • Fysik
  • Physics
  • #notchemistry
  • #notsponsored
  • Zetasizer
  • Malvern
  • #indilaballdayeveryday