Resumé
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Accounts of Chemical Research |
| Vol/bind | 39 |
| Udgave nummer | 5 |
| Sider (fra-til) | 354-361 |
| Antal sider | 8 |
| ISSN | 0001-4842 |
| DOI | |
| Status | Udgivet - 2006 |
| Udgivet eksternt | Ja |
Citer dette
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The phomactins : A novel group of terpenoid platelet activating factor antagonists related biogenetically to the taxanes. / Goldring, W. P. D.; Pattenden, G.
I: Accounts of Chemical Research, Bind 39, Nr. 5, 2006, s. 354-361.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
TY - JOUR
T1 - The phomactins
T2 - A novel group of terpenoid platelet activating factor antagonists related biogenetically to the taxanes
AU - Goldring, W. P. D.
AU - Pattenden, G.
PY - 2006
Y1 - 2006
N2 - A description of the structurally unusual “phomactin” family of platelet activating factor antagonists recently found in the marine fungus Phoma sp. is presented. The phomactins show an interesting structural and biosynthetic relationship with the more familiar taxane group of antitumor compounds isolated from yew trees. The Account highlights and discusses this unique relationship and also presents a cogent picture of plausible biogenetic interrelationships within the family of phomactins. Complementary synthetic endeavors with the phomactins are interwoven in the discussions, alongside contemporaneous biosynthetic studies with both the phomactins and the taxanes.
AB - A description of the structurally unusual “phomactin” family of platelet activating factor antagonists recently found in the marine fungus Phoma sp. is presented. The phomactins show an interesting structural and biosynthetic relationship with the more familiar taxane group of antitumor compounds isolated from yew trees. The Account highlights and discusses this unique relationship and also presents a cogent picture of plausible biogenetic interrelationships within the family of phomactins. Complementary synthetic endeavors with the phomactins are interwoven in the discussions, alongside contemporaneous biosynthetic studies with both the phomactins and the taxanes.
U2 - 10.1021/ar050186c
DO - 10.1021/ar050186c
M3 - Journal article
VL - 39
SP - 354
EP - 361
JO - Accounts of Chemical Research
JF - Accounts of Chemical Research
SN - 0001-4842
IS - 5
ER -