### Resumé

In this chapter we introduce a new term, the "Mathematical Microscope", as a method of using mathematics in accessing information about reality when this information is otherwise inaccessible. Furthermore, we discuss how models and experiments are related: none of which are important without the other. In the sciences and medicine, a link that is often missing in the chain of a system can be made visible with the aid of the mathematical microscope. The mathematical microscope serves not only as a lens to clarify a blurred picture but more important as a tool to unveil profound truths. In reality, models are most often used in a detective-like manner to investigate the consequences of different hypothesis. Thus, models can help clarify connections and relations. Consequently, models also help to reveal mechanisms and to develop theories. Case studies are presented and the role of mathematical modeling is discussed for type 1 and type 2 diabetes, depression, cardiovascular diseases and the interactions between the combinations of these, the so-called gray triangle in the metabolic syndrome.

Originalsprog | Engelsk |
---|---|

Titel | BetaSys : Systems biology of regulated exocytosis in pancreatic β-cells |

Redaktører | Bernhelm Booß-Bavnbek, Beate Klösgen, Jesper Larsen, Flemming Pociot, Erik Renström |

Antal sider | 20 |

Forlag | Springer |

Publikationsdato | 2011 |

Sider | 97-118 |

Kapitel | 6 |

ISBN (Trykt) | 978-1-4419-6955-2 |

Status | Udgivet - 2011 |

Navn | Systems Biology |
---|---|

Vol/bind | 2 |

ISSN | 2191-222X |

### Citer dette

*BetaSys: Systems biology of regulated exocytosis in pancreatic β-cells*(s. 97-118). Springer. Systems Biology, Bind. 2

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*BetaSys: Systems biology of regulated exocytosis in pancreatic β-cells.*Springer, Systems Biology, bind 2, s. 97-118.

**The Mathematical Microscope - Making the inaccessible accessible.** / Ottesen, Johnny T.

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

TY - CHAP

T1 - The Mathematical Microscope - Making the inaccessible accessible

AU - Ottesen, Johnny T.

PY - 2011

Y1 - 2011

N2 - In this chapter we introduce a new term, the "Mathematical Microscope", as a method of using mathematics in accessing information about reality when this information is otherwise inaccessible. Furthermore, we discuss how models and experiments are related: none of which are important without the other. In the sciences and medicine, a link that is often missing in the chain of a system can be made visible with the aid of the mathematical microscope. The mathematical microscope serves not only as a lens to clarify a blurred picture but more important as a tool to unveil profound truths. In reality, models are most often used in a detective-like manner to investigate the consequences of different hypothesis. Thus, models can help clarify connections and relations. Consequently, models also help to reveal mechanisms and to develop theories. Case studies are presented and the role of mathematical modeling is discussed for type 1 and type 2 diabetes, depression, cardiovascular diseases and the interactions between the combinations of these, the so-called gray triangle in the metabolic syndrome.

AB - In this chapter we introduce a new term, the "Mathematical Microscope", as a method of using mathematics in accessing information about reality when this information is otherwise inaccessible. Furthermore, we discuss how models and experiments are related: none of which are important without the other. In the sciences and medicine, a link that is often missing in the chain of a system can be made visible with the aid of the mathematical microscope. The mathematical microscope serves not only as a lens to clarify a blurred picture but more important as a tool to unveil profound truths. In reality, models are most often used in a detective-like manner to investigate the consequences of different hypothesis. Thus, models can help clarify connections and relations. Consequently, models also help to reveal mechanisms and to develop theories. Case studies are presented and the role of mathematical modeling is discussed for type 1 and type 2 diabetes, depression, cardiovascular diseases and the interactions between the combinations of these, the so-called gray triangle in the metabolic syndrome.

KW - Mathematical Modeling

KW - Diabetes

KW - Depression

KW - Cardiovascular Regulation

KW - Systems Biology

KW - Measurements

KW - Experiments

M3 - Book chapter

SN - 978-1-4419-6955-2

SP - 97

EP - 118

BT - BetaSys

A2 - Booß-Bavnbek, Bernhelm

A2 - Klösgen, Beate

A2 - Larsen, Jesper

A2 - Pociot, Flemming

A2 - Renström, Erik

PB - Springer

ER -