Planning interventions to respond to cholera epidemics requires an understanding of the major transmission routes. Interrupting short-cycle (household, foodborne) transmission may require different approaches as compared long-cycle (environmentally-mediated/waterborne) transmission. However, differentiating the relative contribution of short- and long-cycle routes has remained difficult, and most cholera outbreak control efforts focus on interrupting long-cycle transmission. Here we use high-resolution epidemiological and municipal infrastructure data from a cholera outbreak in 1853 Copenhagen to explore the relative contribution of short- and long-cycle transmission routes during a major urban epidemic.
- Water resources
- Simulation and modeling
- Public and occupational health
- Cholera vaccines
- surface water
Phelps, M. D., Azman, A. S., Lewnard, J. A., Antillon, M., Simonsen, L., Andreasen, V., Jensen, P. K. M., & Pitzer, V. E. (2017). The importance of thinking beyond the water-supply in cholera epidemics: A historical urban case-study. P L o S Neglected Tropical Diseases (Online), 11(11), 1-15. [e0006103]. https://doi.org/10.1371/journal.pntd.0006103