Synthesis of macrocyclic lactams and lactones via ring-closing olefin metathesis

W. P. D. Goldring, A. S. Hodder, L. Weiler

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

Lactones and lactams 4–6 were synthesized from a series of acyclic dienes 1–3 via ring-closing olefin metathesis, as shown in equation 1. The geometry of the resulting double bond was determined, and the EIZ ratios compared to values from molecular mechanics calculations.
OriginalsprogEngelsk
TidsskriftTetrahedron Letters
Vol/bind39
Udgave nummer28
Sider (fra-til)4955-4958
Antal sider4
ISSN0040-4039
DOI
StatusUdgivet - 1998
Udgivet eksterntJa

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