Structural studies of chemical constituents of Thithonia Tagetiflora Desv (Asteraceae)

Vinh Ngoc Huynh, Thu Nguyen Thi Hoai, Kim Phi Phung Nguyen, Poul Erik Hansen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Tithonia tagetiflora Desv. (Asteraceae) is a widespread plant in Vietnam, and the species of Tithonia are known as plants containing many biologically active compounds. However, T. tagetiflora's chemical composition remains mostly unknown. Therefore, we now report the structural elucidation of two new sesquiterpene lactones, 8-angeloyloxy-2,14-epoxygermacra-4,10(1),11(13)-trien-6,12-olide (1) and 6-angeloyloxy-1-hydroxy-3,4-epoxygermacra-9,11(13)-dien-8,12-olide (2), together with three known compounds, including two norisoprenoids, (6S,9S)-vomifoliol or (6R,9R)-vomifoliol (3) and (6S,9S)-roseoside (4), and one glutinane type triterpene, epi-glutinol (5), from the leaves of T. tagetiflora. Their structures are established by 1D and 2D NMR spectroscopy, as well as ESI-MS analysis and comparison with literature data
OriginalsprogEngelsk
TidsskriftMagnetic Resonance in Chemistry
Vol/bind51
Udgave nummer7
Sider (fra-til)439-443
Antal sider5
ISSN0749-1581
DOI
StatusUdgivet - 2013

Emneord

  • NMR
  • norisoprenoid
  • sesquiterpene lactone
  • asteraceae

Citer dette

Ngoc Huynh, Vinh ; Nguyen Thi Hoai, Thu ; Phi Phung Nguyen, Kim ; Hansen, Poul Erik. / Structural studies of chemical constituents of Thithonia Tagetiflora Desv (Asteraceae). I: Magnetic Resonance in Chemistry. 2013 ; Bind 51, Nr. 7. s. 439-443.
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abstract = "Tithonia tagetiflora Desv. (Asteraceae) is a widespread plant in Vietnam, and the species of Tithonia are known as plants containing many biologically active compounds. However, T. tagetiflora's chemical composition remains mostly unknown. Therefore, we now report the structural elucidation of two new sesquiterpene lactones, 8-angeloyloxy-2,14-epoxygermacra-4,10(1),11(13)-trien-6,12-olide (1) and 6-angeloyloxy-1-hydroxy-3,4-epoxygermacra-9,11(13)-dien-8,12-olide (2), together with three known compounds, including two norisoprenoids, (6S,9S)-vomifoliol or (6R,9R)-vomifoliol (3) and (6S,9S)-roseoside (4), and one glutinane type triterpene, epi-glutinol (5), from the leaves of T. tagetiflora. Their structures are established by 1D and 2D NMR spectroscopy, as well as ESI-MS analysis and comparison with literature data",
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author = "{Ngoc Huynh}, Vinh and {Nguyen Thi Hoai}, Thu and {Phi Phung Nguyen}, Kim and Hansen, {Poul Erik}",
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Structural studies of chemical constituents of Thithonia Tagetiflora Desv (Asteraceae). / Ngoc Huynh, Vinh; Nguyen Thi Hoai, Thu; Phi Phung Nguyen, Kim; Hansen, Poul Erik.

I: Magnetic Resonance in Chemistry, Bind 51, Nr. 7, 2013, s. 439-443.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Structural studies of chemical constituents of Thithonia Tagetiflora Desv (Asteraceae)

AU - Ngoc Huynh, Vinh

AU - Nguyen Thi Hoai, Thu

AU - Phi Phung Nguyen, Kim

AU - Hansen, Poul Erik

PY - 2013

Y1 - 2013

N2 - Tithonia tagetiflora Desv. (Asteraceae) is a widespread plant in Vietnam, and the species of Tithonia are known as plants containing many biologically active compounds. However, T. tagetiflora's chemical composition remains mostly unknown. Therefore, we now report the structural elucidation of two new sesquiterpene lactones, 8-angeloyloxy-2,14-epoxygermacra-4,10(1),11(13)-trien-6,12-olide (1) and 6-angeloyloxy-1-hydroxy-3,4-epoxygermacra-9,11(13)-dien-8,12-olide (2), together with three known compounds, including two norisoprenoids, (6S,9S)-vomifoliol or (6R,9R)-vomifoliol (3) and (6S,9S)-roseoside (4), and one glutinane type triterpene, epi-glutinol (5), from the leaves of T. tagetiflora. Their structures are established by 1D and 2D NMR spectroscopy, as well as ESI-MS analysis and comparison with literature data

AB - Tithonia tagetiflora Desv. (Asteraceae) is a widespread plant in Vietnam, and the species of Tithonia are known as plants containing many biologically active compounds. However, T. tagetiflora's chemical composition remains mostly unknown. Therefore, we now report the structural elucidation of two new sesquiterpene lactones, 8-angeloyloxy-2,14-epoxygermacra-4,10(1),11(13)-trien-6,12-olide (1) and 6-angeloyloxy-1-hydroxy-3,4-epoxygermacra-9,11(13)-dien-8,12-olide (2), together with three known compounds, including two norisoprenoids, (6S,9S)-vomifoliol or (6R,9R)-vomifoliol (3) and (6S,9S)-roseoside (4), and one glutinane type triterpene, epi-glutinol (5), from the leaves of T. tagetiflora. Their structures are established by 1D and 2D NMR spectroscopy, as well as ESI-MS analysis and comparison with literature data

KW - NMR

KW - norisoprenoid

KW - sesquiterpene lactone

KW - asteraceae

U2 - 10.1002/mrc.3963

DO - 10.1002/mrc.3963

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JO - Magnetic Resonance in Chemistry

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