Structural Studies of β-Diketones and Their Implications on Biological Effects

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Abstract

The paper briefly summarizes methods to determine the structure of β-diketones with emphasis on NMR methods. Density functional calculations are also briefly treated. Emphasis is on the tautomeric equilibria of β-diketones in relation to biological effects. Relevant physical parameters such as acidity and solubility are treated. A series of biologically active molecules are treated with respect to structure (tautomerism). Characteristic molecules or groups of molecules are usnic acids, tetramic and tetronic acids, o-hydroxydibenzoylmethanes, curcumines, lupulones, and hyperforines.
OriginalsprogEngelsk
Artikelnummer1189
TidsskriftPharmaceuticals
Vol/bind14
Udgave nummer11
ISSN1424-8247
DOI
StatusUdgivet - nov. 2021

Bibliografisk note

This article belongs to the Special Issue β-Diketones and Their Derivatives: Synthesis, Characterization and Biomedical Applications

Emneord

  • biological effects
  • DFT calculations
  • tautomerism
  • SAR

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