Apart from a short clarification of what neuro-doping is, the aim of this article is twofold. First to give a few reasons in favour of having a special issue on neuro-doping. Second to present an overview of the articles in this issue. One reason for having this special issue, is that it needs to be established whether methods such as transcranial direct-current stimulation (tDCS) should be added to World Anti-Doping Agency’s (WADA) prohibited list or not, as it is currently under discussion by WADA. Another reason for dealing with the ethics of neuro-doping is that ethical analysis of the use or possible use of neuro-doping in sport is a neglected subject. This issue cover a wide range of ethical analyses of the use of neuro-doping among athletes, chess players, e-gamers and even couch potatoes. For example, whether tDCS ought to be prohibited by WADA and/or the state; or whether its use ought to be promoted by the state; whether the use of neuro-doping is unfair; or whether it should be allowed for businesses to advertise high-sugar, high-caffeine beverages to youngsters.