Small RNA detection method based on small RNA primed xenosensor module amplification

Seong Wook Yang; Seok Keun Cho; Pratik Shah; Riddhi Nitin Nagda

Small RNA detection method based on small RNA primed xenosensor module amplification

Seong Wook Yang (Opfinder), Seok Keun Cho (Opfinder), Pratik Shah (Opfinder), Riddhi Nitin Nagda (Opfinder)

Publikation: Patent

Abstract

The present invention may provide a small RNA detection sensor comprising: at one end thereof, a first sensing region comprising nucleotides having a sequence complementary to target small RNA; and a PCR-capable region that is coupled to the first sensing region, the small RNA detection sensor to synthesize a replication region complementary to the PCR-capable region by a DNA polymerase by using the target small RNA as a primer, and amplify the PCR-capable region and the replication region.

Originalsprog	Engelsk
Patentnummer	US11591646B2
Land/Område	USA
Status	Udgivet - 28 feb. 2023

Link til dokument

https://patents.google.com/patent/US11591646B2/en

Citer dette

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abstract = "The present invention may provide a small RNA detection sensor comprising: at one end thereof, a first sensing region comprising nucleotides having a sequence complementary to target small RNA; and a PCR-capable region that is coupled to the first sensing region, the small RNA detection sensor to synthesize a replication region complementary to the PCR-capable region by a DNA polymerase by using the target small RNA as a primer, and amplify the PCR-capable region and the replication region.",

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AB - The present invention may provide a small RNA detection sensor comprising: at one end thereof, a first sensing region comprising nucleotides having a sequence complementary to target small RNA; and a PCR-capable region that is coupled to the first sensing region, the small RNA detection sensor to synthesize a replication region complementary to the PCR-capable region by a DNA polymerase by using the target small RNA as a primer, and amplify the PCR-capable region and the replication region.

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