TY - JOUR
T1 - Seroincidence of human infections with nontyphoid Salmonella compared with data from public health surveillance and food animals in 13 European countries
AU - Mølbak, Kåre
AU - Simonsen, Jacob
AU - Jørgensen, Charlotte S
AU - Krogfelt, Karen A
AU - Falkenhorst, Gerhard
AU - Ethelberg, Steen
AU - Takkinen, Johanna
AU - Emborg, Hanne-Dorthe
PY - 2014
Y1 - 2014
N2 - We developed a model that enabled a back-calculation of the annual salmonellosis seroincidence from measurements of Salmonella antibodies and applied this model to 9677 serum samples collected from populations in 13 European countries. We found a 10-fold difference in the seroincidence, which was lowest in Sweden (0.06 infections per person-year), Finland (0.07), and Denmark (0.08) and highest in Spain (0.61), followed by Poland (0.55). These numbers were not correlated with the reported national incidence of Salmonella infections in humans but were correlated with prevalence data of Salmonella in laying hens (P < .001), broilers (P < .001), and slaughter pigs (P = .03). Seroincidence also correlated with Swedish data on the country-specific risk of travel-associated Salmonella infections (P = .001). Estimates based on seroepidemiological methods are well suited to measure the force of transmission of Salmonella to human populations, in particular relevant for assessments where data include notifications from areas, states or countries with diverse characteristics of the Salmonella surveillance.
AB - We developed a model that enabled a back-calculation of the annual salmonellosis seroincidence from measurements of Salmonella antibodies and applied this model to 9677 serum samples collected from populations in 13 European countries. We found a 10-fold difference in the seroincidence, which was lowest in Sweden (0.06 infections per person-year), Finland (0.07), and Denmark (0.08) and highest in Spain (0.61), followed by Poland (0.55). These numbers were not correlated with the reported national incidence of Salmonella infections in humans but were correlated with prevalence data of Salmonella in laying hens (P < .001), broilers (P < .001), and slaughter pigs (P = .03). Seroincidence also correlated with Swedish data on the country-specific risk of travel-associated Salmonella infections (P = .001). Estimates based on seroepidemiological methods are well suited to measure the force of transmission of Salmonella to human populations, in particular relevant for assessments where data include notifications from areas, states or countries with diverse characteristics of the Salmonella surveillance.
U2 - 10.1093/cid/ciu627
DO - 10.1093/cid/ciu627
M3 - Journal article
SN - 1058-4838
VL - 59
SP - 1599
EP - 1606
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 11
ER -