Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic

Dominic van der Waals, Leo E. Heim, Simona Vallazza, Christian Gedig, Jan Deska, M. H. G. Prechtl

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

The catalytic networks of methylotrophic organisms, featuring redox enzymes for the activation of one-carbon moieties, can serve as great inspiration in the development of novel homogeneously catalyzed pathways for the interconversion of C-1 molecules at ambient conditions. An imidazolium-tagged arene-ruthenium complex was identified as an effective functional mimic of the bacterial formaldehyde dismutase, which provides a new and highly selective route for the conversion of formaldehyde to methanol in absence of any external reducing agents. Moreover, secondary amines are reductively methylated by the organometallic dismutase mimic in a redox self-sufficient manner with formaldehyde acting both as carbon source and reducing agent.
OriginalsprogEngelsk
TidsskriftChemistry: A European Journal
Vol/bind22
Udgave nummer33
Sider (fra-til)11568-11573
Antal sider6
ISSN0947-6539
DOI
StatusUdgivet - 2016
Udgivet eksterntJa

Citer dette

van der Waals, Dominic ; Heim, Leo E. ; Vallazza, Simona ; Gedig, Christian ; Deska, Jan ; Prechtl, M. H. G. / Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic. I: Chemistry: A European Journal. 2016 ; Bind 22, Nr. 33. s. 11568-11573.
@article{1f0f291412234757ae9acccc025fdbfa,
title = "Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic",
abstract = "The catalytic networks of methylotrophic organisms, featuring redox enzymes for the activation of one-carbon moieties, can serve as great inspiration in the development of novel homogeneously catalyzed pathways for the interconversion of C-1 molecules at ambient conditions. An imidazolium-tagged arene-ruthenium complex was identified as an effective functional mimic of the bacterial formaldehyde dismutase, which provides a new and highly selective route for the conversion of formaldehyde to methanol in absence of any external reducing agents. Moreover, secondary amines are reductively methylated by the organometallic dismutase mimic in a redox self-sufficient manner with formaldehyde acting both as carbon source and reducing agent.",
author = "{van der Waals}, Dominic and Heim, {Leo E.} and Simona Vallazza and Christian Gedig and Jan Deska and Prechtl, {M. H. G.}",
note = "van der Waals, Dominic Heim, Leo E. Vallazza, Simona Gedig, Christian Deska, Jan Prechtl, Martin H. G. Deska, Jan/M-2091-2013 1521-3765",
year = "2016",
doi = "10.1002/chem.201602679",
language = "English",
volume = "22",
pages = "11568--11573",
journal = "Chemistry: A European Journal",
issn = "0947-6539",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "33",

}

Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic. / van der Waals, Dominic; Heim, Leo E.; Vallazza, Simona; Gedig, Christian; Deska, Jan; Prechtl, M. H. G.

I: Chemistry: A European Journal, Bind 22, Nr. 33, 2016, s. 11568-11573.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic

AU - van der Waals, Dominic

AU - Heim, Leo E.

AU - Vallazza, Simona

AU - Gedig, Christian

AU - Deska, Jan

AU - Prechtl, M. H. G.

N1 - van der Waals, Dominic Heim, Leo E. Vallazza, Simona Gedig, Christian Deska, Jan Prechtl, Martin H. G. Deska, Jan/M-2091-2013 1521-3765

PY - 2016

Y1 - 2016

N2 - The catalytic networks of methylotrophic organisms, featuring redox enzymes for the activation of one-carbon moieties, can serve as great inspiration in the development of novel homogeneously catalyzed pathways for the interconversion of C-1 molecules at ambient conditions. An imidazolium-tagged arene-ruthenium complex was identified as an effective functional mimic of the bacterial formaldehyde dismutase, which provides a new and highly selective route for the conversion of formaldehyde to methanol in absence of any external reducing agents. Moreover, secondary amines are reductively methylated by the organometallic dismutase mimic in a redox self-sufficient manner with formaldehyde acting both as carbon source and reducing agent.

AB - The catalytic networks of methylotrophic organisms, featuring redox enzymes for the activation of one-carbon moieties, can serve as great inspiration in the development of novel homogeneously catalyzed pathways for the interconversion of C-1 molecules at ambient conditions. An imidazolium-tagged arene-ruthenium complex was identified as an effective functional mimic of the bacterial formaldehyde dismutase, which provides a new and highly selective route for the conversion of formaldehyde to methanol in absence of any external reducing agents. Moreover, secondary amines are reductively methylated by the organometallic dismutase mimic in a redox self-sufficient manner with formaldehyde acting both as carbon source and reducing agent.

U2 - 10.1002/chem.201602679

DO - 10.1002/chem.201602679

M3 - Journal article

VL - 22

SP - 11568

EP - 11573

JO - Chemistry: A European Journal

JF - Chemistry: A European Journal

SN - 0947-6539

IS - 33

ER -