Maternal pulmonary exposure to ultrafine particles during pregnancy may affect the health of the child. Developmental toxicity of carbon black (Printex 90) nanoparticles was evaluated in a mouse model. Time-mated mice were intratracheally instilled with Printex 90 dispersed in Millipore water on gestation days (GD) 7, 10, 15 and 18, with total doses of 11, 54 and 268 mu g Printex 90/animal. The female offspring prenatally exposed to 268 mu g Printex 90/animal displayed altered habituation pattern during the Open field test.
|Tidsskrift||Basic & Clinical Pharmacology & Toxicology|
|Status||Udgivet - 2011|
Jackson, P., Vogel, U., Wallin, H., & Hougaard, K. S. (2011). Prenatal Exposure to Carbon Black (Printex 90): Effects on Sexual Development and Neurofunction . Basic & Clinical Pharmacology & Toxicology, 109(6), 434-437.