Prenatal Exposure to Carbon Black (Printex 90): Effects on Sexual Development and Neurofunction

Petra Jackson, Ulla Vogel, Håkan Wallin, Karin Sørig Hougaard

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    Abstract

    Maternal pulmonary exposure to ultrafine particles during pregnancy may affect the health of the child. Developmental toxicity of carbon black (Printex 90) nanoparticles was evaluated in a mouse model. Time-mated mice were intratracheally instilled with Printex 90 dispersed in Millipore water on gestation days (GD) 7, 10, 15 and 18, with total doses of 11, 54 and 268 mu g Printex 90/animal. The female offspring prenatally exposed to 268 mu g Printex 90/animal displayed altered habituation pattern during the Open field test.
    OriginalsprogEngelsk
    TidsskriftBasic & Clinical Pharmacology & Toxicology
    Vol/bind109
    Udgave nummer6
    Sider (fra-til)434-437
    ISSN1742-7835
    StatusUdgivet - 2011

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