Pharmacological profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus)

Ming Liu, Poul Erik Hansen, Genzhu Wang , Lin Qiu , Jianjun Dong, Hua Yin, Zhonghua Qian , Mei Yang, Jinlai Miao

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

The female inflorescences of hops (Humulus lupulus L.), a well-known bittering agent used in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is one of the bioactive substances contributing to its medical applications. Among foodstuffs XN is found primarily in beer and its natural occurrence is surveyed. In recent years, XN has received much attention for its biological effects. The present review describes the pharmacological aspects of XN and summarizes the most interesting findings obtained in the preclinical research related to this compound, including the pharmacological activity, the pharmacokinetics, and the safety of XN. Furthermore, the potential use of XN as a food additive considering its many positive biological effects is discussed
OriginalsprogEngelsk
TidsskriftMolecules
Vol/bind20
Udgave nummer1
Sider (fra-til)754-779
Antal sider26
ISSN1420-3049
DOI
StatusUdgivet - jan. 2015

Emneord

  • beer
  • xanthohumol
  • metabolites
  • functional food
  • flavonoids

Citer dette

Liu, Ming ; Hansen, Poul Erik ; Wang , Genzhu ; Qiu , Lin ; Dong, Jianjun ; Yin, Hua ; Qian , Zhonghua ; Yang, Mei ; Miao , Jinlai . / Pharmacological profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus). I: Molecules. 2015 ; Bind 20, Nr. 1. s. 754-779.
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title = "Pharmacological profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus)",
abstract = "The female inflorescences of hops (Humulus lupulus L.), a well-known bittering agent used in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is one of the bioactive substances contributing to its medical applications. Among foodstuffs XN is found primarily in beer and its natural occurrence is surveyed. In recent years, XN has received much attention for its biological effects. The present review describes the pharmacological aspects of XN and summarizes the most interesting findings obtained in the preclinical research related to this compound, including the pharmacological activity, the pharmacokinetics, and the safety of XN. Furthermore, the potential use of XN as a food additive considering its many positive biological effects is discussed",
keywords = "beer, xanthohumol, metabolites, functional food, flavonoids, beer, humulones, hobbs, biological effects, metabolites",
author = "Ming Liu and Hansen, {Poul Erik} and Genzhu Wang and Lin Qiu and Jianjun Dong and Hua Yin and Zhonghua Qian and Mei Yang and Jinlai Miao",
year = "2015",
month = "1",
doi = "10.3390/molecules20010754",
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Liu, M, Hansen, PE, Wang , G, Qiu , L, Dong, J, Yin, H, Qian , Z, Yang, M & Miao , J 2015, 'Pharmacological profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus)', Molecules, bind 20, nr. 1, s. 754-779. https://doi.org/10.3390/molecules20010754

Pharmacological profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus). / Liu, Ming; Hansen, Poul Erik; Wang , Genzhu ; Qiu , Lin; Dong, Jianjun ; Yin, Hua ; Qian , Zhonghua ; Yang, Mei ; Miao , Jinlai .

I: Molecules, Bind 20, Nr. 1, 01.2015, s. 754-779.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Pharmacological profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus)

AU - Liu, Ming

AU - Hansen, Poul Erik

AU - Wang , Genzhu

AU - Qiu , Lin

AU - Dong, Jianjun

AU - Yin, Hua

AU - Qian , Zhonghua

AU - Yang, Mei

AU - Miao , Jinlai

PY - 2015/1

Y1 - 2015/1

N2 - The female inflorescences of hops (Humulus lupulus L.), a well-known bittering agent used in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is one of the bioactive substances contributing to its medical applications. Among foodstuffs XN is found primarily in beer and its natural occurrence is surveyed. In recent years, XN has received much attention for its biological effects. The present review describes the pharmacological aspects of XN and summarizes the most interesting findings obtained in the preclinical research related to this compound, including the pharmacological activity, the pharmacokinetics, and the safety of XN. Furthermore, the potential use of XN as a food additive considering its many positive biological effects is discussed

AB - The female inflorescences of hops (Humulus lupulus L.), a well-known bittering agent used in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is one of the bioactive substances contributing to its medical applications. Among foodstuffs XN is found primarily in beer and its natural occurrence is surveyed. In recent years, XN has received much attention for its biological effects. The present review describes the pharmacological aspects of XN and summarizes the most interesting findings obtained in the preclinical research related to this compound, including the pharmacological activity, the pharmacokinetics, and the safety of XN. Furthermore, the potential use of XN as a food additive considering its many positive biological effects is discussed

KW - beer

KW - xanthohumol

KW - metabolites

KW - functional food

KW - flavonoids

KW - beer

KW - humulones

KW - hobbs

KW - biological effects

KW - metabolites

U2 - 10.3390/molecules20010754

DO - 10.3390/molecules20010754

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JO - Molecules

JF - Molecules

SN - 1420-3049

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