Other age groups than children need to be considered as carriers of Streptococcal pneumoniae serotypes

Hans Christian Slotved*

*Corresponding author

Publikation: Bidrag til tidsskriftKommentar/debatpeer review

Abstract

We need to raise the issue that focus on children as the only carriage group for pneumococci is not optimal; we need to consider that other age groups might also be carriers of pneumococcal serotypes causing invasive pneumococcal diseases (IPD) in unvaccinated age groups. The pneumococcal conjugate vaccines (PCV) have successfully removed IPD from vaccinated children. Studies have shown an effect of PCV reducing the pneumococcal carriage of PCV serotypes in children. The status for several countries having used PCV for many years is that they do not see PCV serotypes neither carried nor as a cause of IPD in children. PCV vaccination of children has shown a herd protection effect in unvaccinated groups as a reduction in IPD cases caused by PCV serotypes. However, not all PCV serotypes have disappeared as the cause of IPD in the unvaccinated age groups. The author therefore believes that if we are to see PCV serotypes disappear as a cause of IPD in unvaccinated age groups, we need to perform further carriage studies to examine carriage in other age groups. Alternatively, all age groups should be vaccinated against pneumococci to eliminate IPD caused by PCV serotypes from possible hidden carriers.

OriginalsprogEngelsk
TidsskriftHuman Vaccines and Immunotherapeutics
Vol/bind12
Udgave nummer10
Sider (fra-til)2670-2674
Antal sider5
ISSN2164-5515
DOI
StatusUdgivet - 2 okt. 2016
Udgivet eksterntJa

Bibliografisk note

Publisher Copyright:
© 2016 Taylor & Francis.

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