Molecular and component volumes of N,N-dimethyl-N-alkylamine N-oxides in DOPC bilayers

Michal Belicka, Maria Klacsova, Janka Karlovska, Peter Westh, Ferdinand Devinsky, Pavol Balgavy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    Resumé

    The volumetric properties of fluid bilayers formed of dioleoylphosphatidylcholine (DOPC) with incorporated N ,N -dimethyl-N -alkylamine N -oxides (Cn NO, n = 6, 10–18 is the even number of carbons in alkyl chain) were studied by vibrating tube densitometry in the temperature interval from 20 °C to 50 °C. It was found that the DOPC and Cn NO mixed ideally in the investigated composition range and hence the molecular volumes of DOPC (V DOPC) and incorporated Cn NO (V CnNO) were constant and additive within error limits. From the temperature dependencies of the molecular volumes of DOPC and Cn NO their coefficients of isobaric thermal expansivities in the investigated temperature interval were obtained. The V CnNO volumes of Cn NO incorporated into DOPC bilayers showed linear dependencies on the Cn NO alkyl chain length at all measured temperatures. This allowed to calculate the component volume of the Cn NO methylene group (VCH2VCH2) at several temperatures and its coefficient of isobaric thermal expansivity. Using the assumption that the component volume of the Cn NO methyl group VCH3=2VCH2VCH3=2VCH2 we also calculated the component volume and the coefficient of isobaric thermal expansivity of the hydrophilic group of Cn NO (V NO). We found that the VCH2VCH2 volume increases in the whole temperature interval whereas the VNO volume decreases
    OriginalsprogEngelsk
    TidsskriftChemistry and Physics of Lipids
    Vol/bind180
    Sider (fra-til)1-6
    ISSN0009-3084
    DOI
    StatusUdgivet - 2014

    Citer dette

    Belicka, Michal ; Klacsova, Maria ; Karlovska, Janka ; Westh, Peter ; Devinsky, Ferdinand ; Balgavy, Pavol. / Molecular and component volumes of N,N-dimethyl-N-alkylamine N-oxides in DOPC bilayers. I: Chemistry and Physics of Lipids. 2014 ; Bind 180. s. 1-6.
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    title = "Molecular and component volumes of N,N-dimethyl-N-alkylamine N-oxides in DOPC bilayers",
    abstract = "The volumetric properties of fluid bilayers formed of dioleoylphosphatidylcholine (DOPC) with incorporated N ,N -dimethyl-N -alkylamine N -oxides (Cn NO, n = 6, 10–18 is the even number of carbons in alkyl chain) were studied by vibrating tube densitometry in the temperature interval from 20 °C to 50 °C. It was found that the DOPC and Cn NO mixed ideally in the investigated composition range and hence the molecular volumes of DOPC (V DOPC) and incorporated Cn NO (V CnNO) were constant and additive within error limits. From the temperature dependencies of the molecular volumes of DOPC and Cn NO their coefficients of isobaric thermal expansivities in the investigated temperature interval were obtained. The V CnNO volumes of Cn NO incorporated into DOPC bilayers showed linear dependencies on the Cn NO alkyl chain length at all measured temperatures. This allowed to calculate the component volume of the Cn NO methylene group (VCH2VCH2) at several temperatures and its coefficient of isobaric thermal expansivity. Using the assumption that the component volume of the Cn NO methyl group VCH3=2VCH2VCH3=2VCH2 we also calculated the component volume and the coefficient of isobaric thermal expansivity of the hydrophilic group of Cn NO (V NO). We found that the VCH2VCH2 volume increases in the whole temperature interval whereas the VNO volume decreases",
    author = "Michal Belicka and Maria Klacsova and Janka Karlovska and Peter Westh and Ferdinand Devinsky and Pavol Balgavy",
    year = "2014",
    doi = "10.1016/j.chemphyslip.2014.02.007",
    language = "English",
    volume = "180",
    pages = "1--6",
    journal = "Chemistry and Physics of Lipids",
    issn = "0009-3084",
    publisher = "Elsevier Ireland Ltd",

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    Molecular and component volumes of N,N-dimethyl-N-alkylamine N-oxides in DOPC bilayers. / Belicka, Michal; Klacsova, Maria; Karlovska, Janka; Westh, Peter; Devinsky, Ferdinand; Balgavy, Pavol.

    I: Chemistry and Physics of Lipids, Bind 180, 2014, s. 1-6.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    TY - JOUR

    T1 - Molecular and component volumes of N,N-dimethyl-N-alkylamine N-oxides in DOPC bilayers

    AU - Belicka, Michal

    AU - Klacsova, Maria

    AU - Karlovska, Janka

    AU - Westh, Peter

    AU - Devinsky, Ferdinand

    AU - Balgavy, Pavol

    PY - 2014

    Y1 - 2014

    N2 - The volumetric properties of fluid bilayers formed of dioleoylphosphatidylcholine (DOPC) with incorporated N ,N -dimethyl-N -alkylamine N -oxides (Cn NO, n = 6, 10–18 is the even number of carbons in alkyl chain) were studied by vibrating tube densitometry in the temperature interval from 20 °C to 50 °C. It was found that the DOPC and Cn NO mixed ideally in the investigated composition range and hence the molecular volumes of DOPC (V DOPC) and incorporated Cn NO (V CnNO) were constant and additive within error limits. From the temperature dependencies of the molecular volumes of DOPC and Cn NO their coefficients of isobaric thermal expansivities in the investigated temperature interval were obtained. The V CnNO volumes of Cn NO incorporated into DOPC bilayers showed linear dependencies on the Cn NO alkyl chain length at all measured temperatures. This allowed to calculate the component volume of the Cn NO methylene group (VCH2VCH2) at several temperatures and its coefficient of isobaric thermal expansivity. Using the assumption that the component volume of the Cn NO methyl group VCH3=2VCH2VCH3=2VCH2 we also calculated the component volume and the coefficient of isobaric thermal expansivity of the hydrophilic group of Cn NO (V NO). We found that the VCH2VCH2 volume increases in the whole temperature interval whereas the VNO volume decreases

    AB - The volumetric properties of fluid bilayers formed of dioleoylphosphatidylcholine (DOPC) with incorporated N ,N -dimethyl-N -alkylamine N -oxides (Cn NO, n = 6, 10–18 is the even number of carbons in alkyl chain) were studied by vibrating tube densitometry in the temperature interval from 20 °C to 50 °C. It was found that the DOPC and Cn NO mixed ideally in the investigated composition range and hence the molecular volumes of DOPC (V DOPC) and incorporated Cn NO (V CnNO) were constant and additive within error limits. From the temperature dependencies of the molecular volumes of DOPC and Cn NO their coefficients of isobaric thermal expansivities in the investigated temperature interval were obtained. The V CnNO volumes of Cn NO incorporated into DOPC bilayers showed linear dependencies on the Cn NO alkyl chain length at all measured temperatures. This allowed to calculate the component volume of the Cn NO methylene group (VCH2VCH2) at several temperatures and its coefficient of isobaric thermal expansivity. Using the assumption that the component volume of the Cn NO methyl group VCH3=2VCH2VCH3=2VCH2 we also calculated the component volume and the coefficient of isobaric thermal expansivity of the hydrophilic group of Cn NO (V NO). We found that the VCH2VCH2 volume increases in the whole temperature interval whereas the VNO volume decreases

    U2 - 10.1016/j.chemphyslip.2014.02.007

    DO - 10.1016/j.chemphyslip.2014.02.007

    M3 - Journal article

    VL - 180

    SP - 1

    EP - 6

    JO - Chemistry and Physics of Lipids

    JF - Chemistry and Physics of Lipids

    SN - 0009-3084

    ER -