Metabolic and functional phenotypic profiling of Drosophila melanogaster reveals reduced sex differentiation under stressful environmental conditions

M. Ørsted, A. Malmendal, J. Muñoz, T.N. Kristensen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Strong sexual dimorphism is commonly observed across species and, e.g., trade-offs between reproduction and maintenance are thought to explain this dimorphism. Here we test how the metabolic and functional phenotypic responses to varying types of environmental stress differ in male and female Drosophila melanogaster (Diptera: Drosophilidae), and how stress impacts the magnitude of sexual dimorphism. Experimental stressors that we exposed flies to during development were heat stress, poor nutrition, high acidity, high levels of ammonia and ethanol. Emerged male and female flies from the different rearing regimes were investigated using nuclear magnetic resonance (NMR) metabolomics and assessed for body mass and viability. Our results showed that environmental stress leads to reduced sexual dimorphism in both metabolic composition and body mass compared to the level of dimorphism observed at benign conditions. This reduced sexual dimorphism in stressful environments might be caused by a lower investment in sex-specific characteristics under such conditions, and our results provide support for the longstanding idea that ecological factors are important for shaping sexual dimorphism and possibly sexual selection.
OriginalsprogEngelsk
TidsskriftBiological Journal of the Linnean Society
Vol/bind123
Udgave nummer1
Sider (fra-til)155-162
ISSN0024-4066
DOI
StatusUdgivet - 2018
Udgivet eksterntJa

Citer dette

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title = "Metabolic and functional phenotypic profiling of Drosophila melanogaster reveals reduced sex differentiation under stressful environmental conditions",
abstract = "Strong sexual dimorphism is commonly observed across species and, e.g., trade-offs between reproduction and maintenance are thought to explain this dimorphism. Here we test how the metabolic and functional phenotypic responses to varying types of environmental stress differ in male and female Drosophila melanogaster (Diptera: Drosophilidae), and how stress impacts the magnitude of sexual dimorphism. Experimental stressors that we exposed flies to during development were heat stress, poor nutrition, high acidity, high levels of ammonia and ethanol. Emerged male and female flies from the different rearing regimes were investigated using nuclear magnetic resonance (NMR) metabolomics and assessed for body mass and viability. Our results showed that environmental stress leads to reduced sexual dimorphism in both metabolic composition and body mass compared to the level of dimorphism observed at benign conditions. This reduced sexual dimorphism in stressful environments might be caused by a lower investment in sex-specific characteristics under such conditions, and our results provide support for the longstanding idea that ecological factors are important for shaping sexual dimorphism and possibly sexual selection.",
keywords = "Drosophila melanogaster, Environmental stress, Functional phenotypes, NMR metabolomics, Sex differentiation",
author = "M. {\O}rsted and A. Malmendal and J. Mu{\~n}oz and T.N. Kristensen",
year = "2018",
doi = "10.1093/biolinnean/blx120",
language = "English",
volume = "123",
pages = "155--162",
journal = "Biological Journal of the Linnean Society",
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Metabolic and functional phenotypic profiling of Drosophila melanogaster reveals reduced sex differentiation under stressful environmental conditions. / Ørsted, M.; Malmendal, A.; Muñoz, J.; Kristensen, T.N.

I: Biological Journal of the Linnean Society, Bind 123, Nr. 1, 2018, s. 155-162.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Metabolic and functional phenotypic profiling of Drosophila melanogaster reveals reduced sex differentiation under stressful environmental conditions

AU - Ørsted, M.

AU - Malmendal, A.

AU - Muñoz, J.

AU - Kristensen, T.N.

PY - 2018

Y1 - 2018

N2 - Strong sexual dimorphism is commonly observed across species and, e.g., trade-offs between reproduction and maintenance are thought to explain this dimorphism. Here we test how the metabolic and functional phenotypic responses to varying types of environmental stress differ in male and female Drosophila melanogaster (Diptera: Drosophilidae), and how stress impacts the magnitude of sexual dimorphism. Experimental stressors that we exposed flies to during development were heat stress, poor nutrition, high acidity, high levels of ammonia and ethanol. Emerged male and female flies from the different rearing regimes were investigated using nuclear magnetic resonance (NMR) metabolomics and assessed for body mass and viability. Our results showed that environmental stress leads to reduced sexual dimorphism in both metabolic composition and body mass compared to the level of dimorphism observed at benign conditions. This reduced sexual dimorphism in stressful environments might be caused by a lower investment in sex-specific characteristics under such conditions, and our results provide support for the longstanding idea that ecological factors are important for shaping sexual dimorphism and possibly sexual selection.

AB - Strong sexual dimorphism is commonly observed across species and, e.g., trade-offs between reproduction and maintenance are thought to explain this dimorphism. Here we test how the metabolic and functional phenotypic responses to varying types of environmental stress differ in male and female Drosophila melanogaster (Diptera: Drosophilidae), and how stress impacts the magnitude of sexual dimorphism. Experimental stressors that we exposed flies to during development were heat stress, poor nutrition, high acidity, high levels of ammonia and ethanol. Emerged male and female flies from the different rearing regimes were investigated using nuclear magnetic resonance (NMR) metabolomics and assessed for body mass and viability. Our results showed that environmental stress leads to reduced sexual dimorphism in both metabolic composition and body mass compared to the level of dimorphism observed at benign conditions. This reduced sexual dimorphism in stressful environments might be caused by a lower investment in sex-specific characteristics under such conditions, and our results provide support for the longstanding idea that ecological factors are important for shaping sexual dimorphism and possibly sexual selection.

KW - Drosophila melanogaster

KW - Environmental stress

KW - Functional phenotypes

KW - NMR metabolomics

KW - Sex differentiation

U2 - 10.1093/biolinnean/blx120

DO - 10.1093/biolinnean/blx120

M3 - Journal article

VL - 123

SP - 155

EP - 162

JO - Biological Journal of the Linnean Society

JF - Biological Journal of the Linnean Society

SN - 0024-4066

IS - 1

ER -