Independent control of replication initiation of the two Vibrio cholerae chromosomes by DnaA and RctB.

Stephane Duigou; Kristine G. Knudsen; Ole Skovgaard; Elisabeth S. Egan; Anders Løbner-Olesen; Matthew K Waldor

doi:10.1128/jb.00565-06

Independent control of replication initiation of the two Vibrio cholerae chromosomes by DnaA and RctB.

Stephane Duigou
, Kristine G. Knudsen
, Ole Skovgaard
, Elisabeth S. Egan
, Anders Løbner-Olesen
, Matthew K Waldor

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

66 Citationer (Scopus)

Abstract

Although the two Vibrio cholerae chromosomes initiate replication in a coordinated fashion, we show here that each chromosome appears to have a specific replication initiator. DnaA overproduction promoted overinitiation of chromosome I and not chromosome II. In contrast, overproduction of RctB, a protein that binds to the origin of replication of chromosome II, promoted overinitiation of chromosome II and not chromosome I.

Originalsprog	Engelsk
Tidsskrift	Journal of Bacteriology
Vol/bind	188
Udgave nummer	17
Sider (fra-til)	6419-24
Antal sider	6
ISSN	0021-9193
DOI	https://doi.org/10.1128/jb.00565-06
Status	Udgivet - 2006

Adgang til dokumentet

10.1128/jb.00565-06

Citationsformater

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title = "Independent control of replication initiation of the two Vibrio cholerae chromosomes by DnaA and RctB.",

abstract = "Although the two Vibrio cholerae chromosomes initiate replication in a coordinated fashion, we show here that each chromosome appears to have a specific replication initiator. DnaA overproduction promoted overinitiation of chromosome I and not chromosome II. In contrast, overproduction of RctB, a protein that binds to the origin of replication of chromosome II, promoted overinitiation of chromosome II and not chromosome I.",

author = "Stephane Duigou and Knudsen, \{Kristine G.\} and Ole Skovgaard and Egan, \{Elisabeth S.\} and Anders L{\o}bner-Olesen and Waldor, \{Matthew K\}",

year = "2006",

doi = "10.1128/jb.00565-06",

language = "English",

volume = "188",

pages = "6419--24",

journal = "Journal of Bacteriology",

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publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Independent control of replication initiation of the two Vibrio cholerae chromosomes by DnaA and RctB.

AU - Duigou, Stephane

AU - Knudsen, Kristine G.

AU - Skovgaard, Ole

AU - Egan, Elisabeth S.

AU - Løbner-Olesen, Anders

AU - Waldor, Matthew K

PY - 2006

Y1 - 2006

N2 - Although the two Vibrio cholerae chromosomes initiate replication in a coordinated fashion, we show here that each chromosome appears to have a specific replication initiator. DnaA overproduction promoted overinitiation of chromosome I and not chromosome II. In contrast, overproduction of RctB, a protein that binds to the origin of replication of chromosome II, promoted overinitiation of chromosome II and not chromosome I.

AB - Although the two Vibrio cholerae chromosomes initiate replication in a coordinated fashion, we show here that each chromosome appears to have a specific replication initiator. DnaA overproduction promoted overinitiation of chromosome I and not chromosome II. In contrast, overproduction of RctB, a protein that binds to the origin of replication of chromosome II, promoted overinitiation of chromosome II and not chromosome I.

U2 - 10.1128/jb.00565-06

DO - 10.1128/jb.00565-06

M3 - Journal article

SN - 0021-9193

VL - 188

SP - 6419

EP - 6424

JO - Journal of Bacteriology

JF - Journal of Bacteriology

IS - 17

ER -