Heat resistance in extended-spectrum beta-lactamase-producing Escherichia coli may favor environmental survival in a hospital setting

Erik J Boll, Jakob Frimodt-Møller, Bente Olesen, Karen A Krogfelt, Carsten Struve

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Nosocomial infections caused by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are a major concern worldwide. There is an urgent need to identify bacterial factors promoting survival and persistence of these organisms in the nosocomial environment. Here, we describe the presence of a gene cluster, containing the Clp ATPase ClpK, within a collection of Danish ESBL-producing E. coli isolates. The cluster conferred thermoprotection upon the isolates, and thus might facilitate survival on medical devices exposed to semi-high temperatures in a hospital setting.

TidsskriftResearch in Microbiology
Udgave nummer5
Sider (fra-til)345-349
Antal sider5
StatusUdgivet - 2016
Udgivet eksterntJa

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