Flat affect and social functioning

a 10 year follow-up study of first episode psychosis patients

Erik Simonsen, Julie Evensen, Jan Ivar Røsberg, Helene Barder, Ulrik Helt Haahr, Wenche ten Welden Hegelstad, Inge Joa, Jan Olav Johannessen, Tor Ketil Larsen, Ingrid Melle, Stein Opjordsmoen, Bjørn Rishovd Rund, Per Vaglum, Thomas McGlashan, Svein Friis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    Resumé

    Background: Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking.
    Objective: The aim of this study was to follow the symptom development of flat affect (FA), over a 10 year follow-up period, with focus on prevalence, predictors and outcome factors including social functioning.
    Methods: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10 years. Patients were grouped as having never-present, improving, deteriorating, fluctuating
    or enduring FA. The groups were compared on baseline variables, variables at 10 year follow-up, and social functioning throughout the follow-up period.
    Results: Twenty nine percent never displayed FA, 66% had improving, deteriorating or fluctuating FA, while 5% of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring,
    fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning over the 10 year period.
    Conclusions: FA is expressed at some point of time in the majority of FEP patients in a 10 year follow-up period, and appears more fluctuant than expected from the relevant literature. FA is associated with poorer outcome
    after 10 years, and enduring FA to poorer social function at all points of assessment.
    OriginalsprogEngelsk
    TidsskriftSchizophrenia Research
    Vol/bind139
    Udgave nummer1-3
    Sider (fra-til)99-104
    ISSN0920-9964
    DOI
    StatusUdgivet - 2012

    Emneord

    • Negative symptoms
    • Flat affect
    • outcome
    • First episode psychosis

    Citer dette

    Simonsen, E., Evensen, J., Røsberg, J. I., Barder, H., Haahr, U. H., Hegelstad, W. T. W., ... Friis, S. (2012). Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients. Schizophrenia Research, 139(1-3), 99-104. https://doi.org/10.1016/j.schres.2012.04.019
    Simonsen, Erik ; Evensen, Julie ; Røsberg, Jan Ivar ; Barder, Helene ; Haahr, Ulrik Helt ; Hegelstad, Wenche ten Welden ; Joa, Inge ; Johannessen, Jan Olav ; Larsen, Tor Ketil ; Melle, Ingrid ; Opjordsmoen, Stein ; Rund, Bjørn Rishovd ; Vaglum, Per ; McGlashan, Thomas ; Friis, Svein. / Flat affect and social functioning : a 10 year follow-up study of first episode psychosis patients. I: Schizophrenia Research. 2012 ; Bind 139, Nr. 1-3. s. 99-104.
    @article{40931b71397442fea86c2cfc7e71d0e1,
    title = "Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients",
    abstract = "Background: Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking.Objective: The aim of this study was to follow the symptom development of flat affect (FA), over a 10 year follow-up period, with focus on prevalence, predictors and outcome factors including social functioning.Methods: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10 years. Patients were grouped as having never-present, improving, deteriorating, fluctuatingor enduring FA. The groups were compared on baseline variables, variables at 10 year follow-up, and social functioning throughout the follow-up period.Results: Twenty nine percent never displayed FA, 66{\%} had improving, deteriorating or fluctuating FA, while 5{\%} of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring,fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning over the 10 year period.Conclusions: FA is expressed at some point of time in the majority of FEP patients in a 10 year follow-up period, and appears more fluctuant than expected from the relevant literature. FA is associated with poorer outcome after 10 years, and enduring FA to poorer social function at all points of assessment.",
    keywords = "Negative symptoms, Flat affect, outcome, First episode psychosis",
    author = "Erik Simonsen and Julie Evensen and R{\o}sberg, {Jan Ivar} and Helene Barder and Haahr, {Ulrik Helt} and Hegelstad, {Wenche ten Welden} and Inge Joa and Johannessen, {Jan Olav} and Larsen, {Tor Ketil} and Ingrid Melle and Stein Opjordsmoen and Rund, {Bj{\o}rn Rishovd} and Per Vaglum and Thomas McGlashan and Svein Friis",
    year = "2012",
    doi = "10.1016/j.schres.2012.04.019",
    language = "English",
    volume = "139",
    pages = "99--104",
    journal = "Schizophrenia Research",
    issn = "0920-9964",
    publisher = "Elsevier BV",
    number = "1-3",

    }

    Simonsen, E, Evensen, J, Røsberg, JI, Barder, H, Haahr, UH, Hegelstad, WTW, Joa, I, Johannessen, JO, Larsen, TK, Melle, I, Opjordsmoen, S, Rund, BR, Vaglum, P, McGlashan, T & Friis, S 2012, 'Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients', Schizophrenia Research, bind 139, nr. 1-3, s. 99-104. https://doi.org/10.1016/j.schres.2012.04.019

    Flat affect and social functioning : a 10 year follow-up study of first episode psychosis patients. / Simonsen, Erik; Evensen, Julie; Røsberg, Jan Ivar; Barder, Helene; Haahr, Ulrik Helt; Hegelstad, Wenche ten Welden; Joa, Inge; Johannessen, Jan Olav; Larsen, Tor Ketil; Melle, Ingrid; Opjordsmoen, Stein; Rund, Bjørn Rishovd; Vaglum, Per; McGlashan, Thomas; Friis, Svein.

    I: Schizophrenia Research, Bind 139, Nr. 1-3, 2012, s. 99-104.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    TY - JOUR

    T1 - Flat affect and social functioning

    T2 - a 10 year follow-up study of first episode psychosis patients

    AU - Simonsen, Erik

    AU - Evensen, Julie

    AU - Røsberg, Jan Ivar

    AU - Barder, Helene

    AU - Haahr, Ulrik Helt

    AU - Hegelstad, Wenche ten Welden

    AU - Joa, Inge

    AU - Johannessen, Jan Olav

    AU - Larsen, Tor Ketil

    AU - Melle, Ingrid

    AU - Opjordsmoen, Stein

    AU - Rund, Bjørn Rishovd

    AU - Vaglum, Per

    AU - McGlashan, Thomas

    AU - Friis, Svein

    PY - 2012

    Y1 - 2012

    N2 - Background: Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking.Objective: The aim of this study was to follow the symptom development of flat affect (FA), over a 10 year follow-up period, with focus on prevalence, predictors and outcome factors including social functioning.Methods: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10 years. Patients were grouped as having never-present, improving, deteriorating, fluctuatingor enduring FA. The groups were compared on baseline variables, variables at 10 year follow-up, and social functioning throughout the follow-up period.Results: Twenty nine percent never displayed FA, 66% had improving, deteriorating or fluctuating FA, while 5% of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring,fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning over the 10 year period.Conclusions: FA is expressed at some point of time in the majority of FEP patients in a 10 year follow-up period, and appears more fluctuant than expected from the relevant literature. FA is associated with poorer outcome after 10 years, and enduring FA to poorer social function at all points of assessment.

    AB - Background: Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking.Objective: The aim of this study was to follow the symptom development of flat affect (FA), over a 10 year follow-up period, with focus on prevalence, predictors and outcome factors including social functioning.Methods: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10 years. Patients were grouped as having never-present, improving, deteriorating, fluctuatingor enduring FA. The groups were compared on baseline variables, variables at 10 year follow-up, and social functioning throughout the follow-up period.Results: Twenty nine percent never displayed FA, 66% had improving, deteriorating or fluctuating FA, while 5% of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring,fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning over the 10 year period.Conclusions: FA is expressed at some point of time in the majority of FEP patients in a 10 year follow-up period, and appears more fluctuant than expected from the relevant literature. FA is associated with poorer outcome after 10 years, and enduring FA to poorer social function at all points of assessment.

    KW - Negative symptoms

    KW - Flat affect

    KW - outcome

    KW - First episode psychosis

    U2 - 10.1016/j.schres.2012.04.019

    DO - 10.1016/j.schres.2012.04.019

    M3 - Journal article

    VL - 139

    SP - 99

    EP - 104

    JO - Schizophrenia Research

    JF - Schizophrenia Research

    SN - 0920-9964

    IS - 1-3

    ER -