Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients

Erik Simonsen, Julie Evensen, Jan Ivar Røsberg, Helene Barder, Ulrik Helt Haahr, Wenche ten Welden Hegelstad, Inge Joa, Jan Olav Johannessen, Tor Ketil Larsen, Ingrid Melle, Stein Opjordsmoen, Bjørn Rishovd Rund, Per Vaglum, Thomas McGlashan, Svein Friis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    Abstract

    Background: Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking.
    Objective: The aim of this study was to follow the symptom development of flat affect (FA), over a 10 year follow-up period, with focus on prevalence, predictors and outcome factors including social functioning.
    Methods: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10 years. Patients were grouped as having never-present, improving, deteriorating, fluctuating
    or enduring FA. The groups were compared on baseline variables, variables at 10 year follow-up, and social functioning throughout the follow-up period.
    Results: Twenty nine percent never displayed FA, 66% had improving, deteriorating or fluctuating FA, while 5% of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring,
    fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning over the 10 year period.
    Conclusions: FA is expressed at some point of time in the majority of FEP patients in a 10 year follow-up period, and appears more fluctuant than expected from the relevant literature. FA is associated with poorer outcome
    after 10 years, and enduring FA to poorer social function at all points of assessment.
    OriginalsprogEngelsk
    TidsskriftSchizophrenia Research
    Vol/bind139
    Udgave nummer1-3
    Sider (fra-til)99-104
    ISSN0920-9964
    DOI
    StatusUdgivet - 2012

    Emneord

    • Negative symptoms
    • Flat affect
    • outcome
    • First episode psychosis

    Citer dette

    Simonsen, E., Evensen, J., Røsberg, J. I., Barder, H., Haahr, U. H., Hegelstad, W. T. W., Joa, I., Johannessen, J. O., Larsen, T. K., Melle, I., Opjordsmoen, S., Rund, B. R., Vaglum, P., McGlashan, T., & Friis, S. (2012). Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients. Schizophrenia Research, 139(1-3), 99-104. https://doi.org/10.1016/j.schres.2012.04.019