The role played by the regional tectonics and relationships between volcanic structures and their shallow magmatic feeding system are of paramount importance in understanding multiple lateral collapse events and, thus, for hazard assessment in active volcanoes. Ollague (21 degrees 18'S, 68 degrees 11'W, Andean Central Volcanic Zone, Chile-Bolivia border) is an active, andesite-dacite, composite volcano developed on a regional NW-striking extensional fault system that bisects the volcanic edifice. Geological and stratigraphic studies on the summit part of the cone, together with new Ar-40/Ar-39 dating and petrographic and geochemical (major-trace elements) analyses, have allowed us to delineate the volcanic history of Ollague and recognize multiple deformation and lateral collapse events. The evolution of Ollague appears to be characterized by four stages of volcano building, separated by three main events of deformation of the cone. These deformation events developed progressively by downthrow of the SW sector of the volcano (similar to 800 ka), along the NW-striking normal fault propagating from the substrate, to a final catastrophic failure (similar to 300 ka) of the SW sector and debris avalanche emplacement. Both NW-trending regional tectonics and weakness of the edifice caused by the successive deformation and collapse events are responsible for both the geometric variations of the shallow magma feeding system and the coexistence of summit and parasitic dacitic vents. Central and lateral vents shifted in a SW-trending direction, i.e. perpendicular to the tectonic trend and along the axis of the collapse movement, and developed along a NW-trending alignment, i.e. parallel to the main tectonic trend and collapse scarps.