Efficient Friedel-Crafts benzoylation of aniline derivatives with 4-fluorobenzoyl chloride using copper triflate in the synthesis of aminobenzophenones

Phuong Hoang Tran, Huy Quang Phung, Poul Erik Hansen, Hai Ngoc Tran, Thach Ngoc Le

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review


An efficient pathway for the synthesis of the aminobenzophenone
derivatives via Friedel–Crafts benzoylation using copper triflate as
catalyst is proposed. New derivatives are synthesized. The copper
triflate could be easily recovered and reused without loss of catalytic
activity. Both the use of ionic liquids and microwave heating turned
out to be fruitful.
TidsskriftSynthetic Communications
Udgave nummer10
StatusUdgivet - 2016

Bibliografisk note

Imortant note from the Publisher regarding the attached document:
“This is an Accepted Manuscript of an article published by Taylor & Francis in Synthetic Communication on 03 Jun 2016, available online: http://www.tandfonline.com/10.1080/00397911.2016.1148164.”


  • Friedel-Crafts acylation
  • microwave

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