Direct synthesis of sulfinic esters via ultrasound accelerated tandem reaction of thiols and alcohols with N-bromosuccinimide

Lan Anh Thi Nguyen, Tri Nghia Le, Cong Thang Duong, Chi Tam Vo, Fritz Duus, Thi Xuan Thi Luu*

*Corresponding author

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The direct transformation of various thiols and simple alcohols with N-bromosuccinimide into sulfinic esters has been investigated by using different categories of base/acidic catalysts as well as co-solvents under varied reaction conditions. The reaction was found out to afford the sulfinic esters with high yields in the absence of catalysts, especially within the shorter time under the acceleration of ultrasonic irradiation than under the longer-lasting conventional stirring conditions.

TidsskriftJournal of Sulfur Chemistry
Udgave nummer5
Sider (fra-til)519-528
Antal sider10
StatusUdgivet - 2021


  • N-bromosuccinimide
  • sulfinic esters
  • tandem reaction
  • Thiols
  • ultrasound irradiation

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