Conceptual model for improving the link between exposure and effects in the aquatic risk assessment of pesticides

JJTI Boesten, H Koepp, PI Adriaanse, TCM Brock, Valery E. Forbes

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

It has been claimed that bisphenol A (BPA) induces superfeminization in the freshwater gastropod, Marisa cornuarietis. To explore the reproducibility of prior work, here we present results from a three-laboratory study, the objectives of which were to determine the mean and variability in test endpoints (i.e., adult fecundity, egg hatchability, and juvenile growth) under baseline conditions and to identify the sources of variability. A major source of variability for all of the measured endpoints was due to differences within and among individuals. With few exceptions, variability among laboratories and among replicate tanks within laboratories contributed little to the observed variability in endpoints. The results highlight the importance of obtaining basic knowledge of husbandry requirements and baseline information on life-history traits of potential test species prior to designing toxicity test protocols. Understanding of the levels and sources of endpoint variability is essential so that statistically robust and ecologically relevant tests of chemicals can be conducted
OriginalsprogEngelsk
TidsskriftEcotoxicology and Environmental Safety
Vol/bind66
Udgave nummer3
Sider (fra-til)291-308
Antal sider18
ISSN0147-6513
DOI
StatusUdgivet - 2007

Citer dette

Boesten, JJTI ; Koepp, H ; Adriaanse, PI ; Brock, TCM ; Forbes, Valery E. / Conceptual model for improving the link between exposure and effects in the aquatic risk assessment of pesticides. I: Ecotoxicology and Environmental Safety. 2007 ; Bind 66, Nr. 3. s. 291-308.
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title = "Conceptual model for improving the link between exposure and effects in the aquatic risk assessment of pesticides",
abstract = "It has been claimed that bisphenol A (BPA) induces superfeminization in the freshwater gastropod, Marisa cornuarietis. To explore the reproducibility of prior work, here we present results from a three-laboratory study, the objectives of which were to determine the mean and variability in test endpoints (i.e., adult fecundity, egg hatchability, and juvenile growth) under baseline conditions and to identify the sources of variability. A major source of variability for all of the measured endpoints was due to differences within and among individuals. With few exceptions, variability among laboratories and among replicate tanks within laboratories contributed little to the observed variability in endpoints. The results highlight the importance of obtaining basic knowledge of husbandry requirements and baseline information on life-history traits of potential test species prior to designing toxicity test protocols. Understanding of the levels and sources of endpoint variability is essential so that statistically robust and ecologically relevant tests of chemicals can be conducted",
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Conceptual model for improving the link between exposure and effects in the aquatic risk assessment of pesticides. / Boesten, JJTI; Koepp, H; Adriaanse, PI; Brock, TCM; Forbes, Valery E.

I: Ecotoxicology and Environmental Safety, Bind 66, Nr. 3, 2007, s. 291-308.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Conceptual model for improving the link between exposure and effects in the aquatic risk assessment of pesticides

AU - Boesten, JJTI

AU - Koepp, H

AU - Adriaanse, PI

AU - Brock, TCM

AU - Forbes, Valery E.

PY - 2007

Y1 - 2007

N2 - It has been claimed that bisphenol A (BPA) induces superfeminization in the freshwater gastropod, Marisa cornuarietis. To explore the reproducibility of prior work, here we present results from a three-laboratory study, the objectives of which were to determine the mean and variability in test endpoints (i.e., adult fecundity, egg hatchability, and juvenile growth) under baseline conditions and to identify the sources of variability. A major source of variability for all of the measured endpoints was due to differences within and among individuals. With few exceptions, variability among laboratories and among replicate tanks within laboratories contributed little to the observed variability in endpoints. The results highlight the importance of obtaining basic knowledge of husbandry requirements and baseline information on life-history traits of potential test species prior to designing toxicity test protocols. Understanding of the levels and sources of endpoint variability is essential so that statistically robust and ecologically relevant tests of chemicals can be conducted

AB - It has been claimed that bisphenol A (BPA) induces superfeminization in the freshwater gastropod, Marisa cornuarietis. To explore the reproducibility of prior work, here we present results from a three-laboratory study, the objectives of which were to determine the mean and variability in test endpoints (i.e., adult fecundity, egg hatchability, and juvenile growth) under baseline conditions and to identify the sources of variability. A major source of variability for all of the measured endpoints was due to differences within and among individuals. With few exceptions, variability among laboratories and among replicate tanks within laboratories contributed little to the observed variability in endpoints. The results highlight the importance of obtaining basic knowledge of husbandry requirements and baseline information on life-history traits of potential test species prior to designing toxicity test protocols. Understanding of the levels and sources of endpoint variability is essential so that statistically robust and ecologically relevant tests of chemicals can be conducted

KW - Endocrine disruption

KW - Gastropod

KW - Reproduction

KW - Risk assessment

KW - Test design

U2 - doi:10.1016/j.ecoenv.2006.10.014

DO - doi:10.1016/j.ecoenv.2006.10.014

M3 - Journal article

VL - 66

SP - 291

EP - 308

JO - Ecotoxicology and Environmental Safety

JF - Ecotoxicology and Environmental Safety

SN - 0147-6513

IS - 3

ER -