Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome

George D Vavougios; Marianthi Breza; Sotirios Zarogiannis; Karen A Krogfelt; Sygkliti-Henrietta Pelidou; Triantafyllos Doskas

Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome

George D Vavougios, Marianthi Breza, Sotirios Zarogiannis, Karen A Krogfelt, Sygkliti-Henrietta Pelidou, Triantafyllos Doskas

Publikation: Konferencebidrag › Poster › Forskning › peer review

Abstract

It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.

Originalsprog	Engelsk
Publikationsdato	2020
Status	Udgivet - 2020
Begivenhed	6th Congress of the European Academy of Neurology (Online) - Online, Paris, Frankrig Varighed: 23 maj 2020 → 26 maj 2020 Konferencens nummer: 6 https://www.ean.org/congress-2020

Konference

Konference	6th Congress of the European Academy of Neurology (Online)
Nummer	6
Lokation	Online
Land/Område	Frankrig
By	Paris
Periode	23/05/2020 → 26/05/2020
Internetadresse	https://www.ean.org/congress-2020

Link til dokument

https://www.researchgate.net/publication/341868049_Comparative_transcriptomics_of_multiple_sclerosis_vs_Viral_infections_common_roles_for_nuclear_transport_neuroactive_peptide_signalling_and_the_spliceosome

Citer dette

Vavougios, G. D., Breza, M., Zarogiannis, S., Krogfelt, K. A., Pelidou, S-H., & Doskas, T. (2020). Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome. Poster session præsenteret på 6th Congress of the European Academy of Neurology (Online), Paris, Frankrig. https://www.researchgate.net/publication/341868049_Comparative_transcriptomics_of_multiple_sclerosis_vs_Viral_infections_common_roles_for_nuclear_transport_neuroactive_peptide_signalling_and_the_spliceosome

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abstract = "It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.",

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Vavougios, GD, Breza, M, Zarogiannis, S, Krogfelt, KA, Pelidou, S-H & Doskas, T 2020, 'Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome', 6th Congress of the European Academy of Neurology (Online), Paris, Frankrig, 23/05/2020 - 26/05/2020. <https://www.researchgate.net/publication/341868049_Comparative_transcriptomics_of_multiple_sclerosis_vs_Viral_infections_common_roles_for_nuclear_transport_neuroactive_peptide_signalling_and_the_spliceosome>

Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome. / Vavougios, George D; Breza, Marianthi; Zarogiannis, Sotirios et al.
2020. Poster session præsenteret på 6th Congress of the European Academy of Neurology (Online), Paris, Frankrig.

Publikation: Konferencebidrag › Poster › Forskning › peer review

TY - CONF

T1 - Comparative transcriptomics of multiple sclerosis vs. Viral infections

T2 - 6th Congress of the European Academy of Neurology (Online)

AU - Vavougios, George D

AU - Breza, Marianthi

AU - Zarogiannis, Sotirios

AU - Krogfelt, Karen A

AU - Pelidou, Sygkliti-Henrietta

AU - Doskas, Triantafyllos

N1 - Conference code: 6

PY - 2020

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N2 - It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.

AB - It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.

M3 - Poster

Y2 - 23 May 2020 through 26 May 2020

ER -