Comparative transcriptomics of multiple sclerosis vs. Viral infections: common roles for nuclear transport, neuroactive peptide signaling and the spliceosome

George D Vavougios, Marianthi Breza, Sotirios Zarogiannis, Karen A Krogfelt, Henrietta--Sygkliti Pelidou, Triantafyllos Doskas

Publikation: KonferencebidragPosterForskningpeer review

Abstract

It is well known that viral infections play an important role in triggering the onset of multiple sclerosis in genetically susceptible individuals. In this study, we try to find common pathways between multiple sclerosis and viral infections by means of a GEO (Gene Expression Omnibus) database. Our results indicate a response to infection phenotype in MS PBMCs, associated with alternative splitting and disruptions of transcriptional homeostasis.
OriginalsprogEngelsk
Publikationsdato2020
StatusUdgivet - 2020
Begivenhed6th Congress of the European Academy of Neurology - Online, Paris, Frankrig
Varighed: 23 maj 202026 maj 2020
https://www.ean.org/congress-2020

Konference

Konference6th Congress of the European Academy of Neurology
LokationOnline
LandFrankrig
ByParis
Periode23/05/202026/05/2020
Internetadresse

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