Characterization and Micellization of a Poloxamer Block Copolymer

Søren Hvidt; Walther Batsberg

doi:10.1080/10236660601094093

Characterization and Micellization of a Poloxamer Block Copolymer

Søren Hvidt, Walther Batsberg

Kemi

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

Several poloxamers that are symmetrical EPE block copolymers (E and P are ethylene and propylene oxide, respectively) have been characterized by size exclusion chromatography on Superose columns in water. The poloxamers contain between 12 and 26 wt% of smaller-size UV-absorbing impurities. Poloxamer P94 (E28P48E28) forms micelles with increasing temperature, and micellization was investigated by eluent gel permeation chromatography (EGPC). EGPC results demonstrate that P94 impurities are not incorporated into the micelles up to 38°C. The importance of poloxamer heterogeneity for thermodynamic and structural studies is discussed.

Originalsprog	Engelsk
Tidsskrift	International Journal of Polymer Analysis & Characterization
Vol/bind	12
Udgave nummer	1
Sider (fra-til)	13-22
Antal sider	10
ISSN	1023-666X
DOI	https://doi.org/10.1080/10236660601094093
Status	Udgivet - 2007

Link til dokument

10.1080/10236660601094093

Citer dette

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