An efficient and green synthesis of 1-indanone and 1-tetralone via intramolecular Friedel-Crafts acylation reaction

Phuong Hoang Tran, Vy Hieu Huynh, Poul Erik Hansen, Duy-Khiem Nguyen Chau, Thach Ngoc Le

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review


Metal-triflate-catalyzed intramolecular Friedel–Crafts acylation of 3-arylpropanoic and 4-arylbutanoic acids in triflate-anion ionic liquids under monomodal microwave irradiation is reported. The environmentally benign synthetic procedure allows the formation of cyclic ketones in good yields within a short reaction time. The catalytic metal triflate in triflate-anion ionic liquids can be easily recovered and reused several times without significant loss of the catalytic performance.
TidsskriftAsian Journal of Organic Chemistry
Udgave nummer5
Sider (fra-til)482-86.
Antal sider5
StatusUdgivet - 2015


  • Friedel-Crafts
  • Cyclisation
  • metal triflate
  • Ionic liquid
  • indanone
  • tetralone

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