Amide versus amine ligand paradigm in the direct amination of alcohols with Ru-PNP complexes

Dennis Pingen, Jong-Hoo Choi, Henry Allen, George Murray, Prasad Ganji, Piet W. N. M. Van Leeuwen, Martin H. G. Prechtl, Dieter Vogt

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

The catalytic activity of a series of Ru-PNP pincer ligand complexes was studied in the direct amination of alcohols with ammonia. It turned out that all complexes of PNP ligands bearing a secondary amine showed no activity in this hydrogen-shuttling reaction sequence, while all complexes of homologous ligands bearing a tertiary amine gave active catalysts. Further comparative studies on catalysts bearing an acridine-based PNP pincer ligand and a PNP ligand of the Xantphos family provided valuable mechanistic insight that led to the design of a highly active catalyst. It appears that in the group of ligands studied here only ligands that do not form stable Ru-amido complexes are active alcohol amination catalysts.
OriginalsprogEngelsk
TidsskriftCatalysis Science & Technology
Vol/bind8
Udgave nummer15
Sider (fra-til)3969-3976
ISSN2044-4753
DOI
StatusUdgivet - 2018
Udgivet eksterntJa

Citer dette

Pingen, D., Choi, J-H., Allen, H., Murray, G., Ganji, P., Van Leeuwen, P. W. N. M., Prechtl, M. H. G., & Vogt, D. (2018). Amide versus amine ligand paradigm in the direct amination of alcohols with Ru-PNP complexes. Catalysis Science & Technology, 8(15), 3969-3976. https://doi.org/10.1039/c8cy00869h