A total synthesis of phomactin A

W. P. D. Goldring, G. Pattenden

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

A total synthesis of phomactin A (1) based on a Cr(II)/Ni(II) macrocyclisation from the aldehyde vinyl iodide 11, leading to 12, followed by elaboration of the epoxyketone 16, which then undergoes spontaneous pyran-hemiacetal formation on deprotection, is described.


Graphical abstract: A total synthesis of phomactin A
OriginalsprogEngelsk
TidsskriftChemical Communications
Udgave nummer16
Sider (fra-til)1736-1737
Antal sider2
ISSN1359-7345
DOI
StatusUdgivet - 2002
Udgivet eksterntJa

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