A Synthesis of (S)-(-)-Umbelactone and Related alpha,beta-Butenolides

W. P. D. Goldring, J. Mann, P. Brockbank

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The development of an asymmetric route for the synthesis of α,β-butenolide building blocks, starting from commercially available d-mannitol, is described. The devised route was applied to a synthesis of the (S)-(-)-enantiomer of the antiviral natural product umbelactone, together with the construction of other synthetically useful lactone structures.
TidsskriftSYNLETT: Accounts and Rapid Communications in Chemical Synthesis
Udgave nummer4
Sider (fra-til)547-550
Antal sider4
StatusUdgivet - 2010
Udgivet eksterntJa

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