A Synthesis of (S)-(-)-Umbelactone and Related alpha,beta-Butenolides

W. P. D. Goldring; J. Mann; P. Brockbank

doi:10.1055/s-0029-1219181

A Synthesis of (S)-(-)-Umbelactone and Related alpha,beta-Butenolides

W. P. D. Goldring, J. Mann, P. Brockbank

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

The development of an asymmetric route for the synthesis of α,β-butenolide building blocks, starting from commercially available d-mannitol, is described. The devised route was applied to a synthesis of the (S)-(-)-enantiomer of the antiviral natural product umbelactone, together with the construction of other synthetically useful lactone structures.

Originalsprog	Engelsk
Tidsskrift	SYNLETT: Accounts and Rapid Communications in Chemical Synthesis
Udgave nummer	4
Sider (fra-til)	547-550
Antal sider	4
ISSN	0936-5214
DOI	https://doi.org/10.1055/s-0029-1219181
Status	Udgivet - 2010
Udgivet eksternt	Ja

Link til dokument

10.1055/s-0029-1219181

Citer dette

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abstract = "The development of an asymmetric route for the synthesis of α,β-butenolide building blocks, starting from commercially available d-mannitol, is described. The devised route was applied to a synthesis of the (S)-(-)-enantiomer of the antiviral natural product umbelactone, together with the construction of other synthetically useful lactone structures.",

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AU - Goldring, W. P. D.

AU - Mann, J.

AU - Brockbank, P.

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N2 - The development of an asymmetric route for the synthesis of α,β-butenolide building blocks, starting from commercially available d-mannitol, is described. The devised route was applied to a synthesis of the (S)-(-)-enantiomer of the antiviral natural product umbelactone, together with the construction of other synthetically useful lactone structures.

AB - The development of an asymmetric route for the synthesis of α,β-butenolide building blocks, starting from commercially available d-mannitol, is described. The devised route was applied to a synthesis of the (S)-(-)-enantiomer of the antiviral natural product umbelactone, together with the construction of other synthetically useful lactone structures.

U2 - 10.1055/s-0029-1219181

DO - 10.1055/s-0029-1219181

M3 - Journal article

SN - 0936-5214

SP - 547

EP - 550

JO - SYNLETT: Accounts and Rapid Communications in Chemical Synthesis

JF - SYNLETT: Accounts and Rapid Communications in Chemical Synthesis

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