A New Flavone Glycoside from Lumnitzera littorea with in vitro α-Glucosidase Inhibitory Activity

Thuy L.T. Nguyen; Thuy T. Pham; Tung T. Bui; Loc T. Huynh; Dang T.T. Truong; Ngoc L. Le; Duc X.  Nguyen; Dung L. Le; Poul Erik Hansen; K. P. Phung Nguyen

doi:10.1177/1934578X19851361

A New Flavone Glycoside from Lumnitzera littorea with in vitro α-Glucosidase Inhibitory Activity

Thuy L.T. Nguyen, Thuy T. Pham, Tung T. Bui, Loc T. Huynh, Dang T.T. Truong, Ngoc L. Le, Duc X. Nguyen, Dung L. Le, Poul Erik Hansen, K. P. Phung Nguyen

Institut for Naturvidenskab og Miljø

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

A new flavone glycoside, lumnitzerone (1), was isolated from leaves of Lumnitzera littorea, together with 9 known flavonoids. Their structures were elucidated by spectroscopic (one-dimensional, two-dimensional nuclear magnetic resonance) and high-resolution mass spectrometry analysis, and comparison with literature data. Extracts and all isolated compounds were evaluated for α-glucosidase inhibitory activity; all the extracts and most of the isolated compounds exhibited better activities than the positive control acarbose.

Originalsprog	Engelsk
Tidsskrift	Natural Product Communications
Vol/bind	14
Udgave nummer	6
Sider (fra-til)	1-5
Antal sider	5
ISSN	1934-578X
DOI	https://doi.org/10.1177/1934578X19851361
Status	Udgivet - 1 maj 2019

Emneord

flavonoid
glucosidase inhibitor
mangrove

Link til dokument

10.1177/1934578X19851361Licens: CC BY-NC-ND

A New Flavone Glycoside From Lumnitzera littorea with In Vitro α-Glucosidase Inhibitory ActivityForlagets udgivne version, 449 KBLicens: CC BY-NC-ND

Citer dette

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title = "A New Flavone Glycoside from Lumnitzera littorea with in vitro α-Glucosidase Inhibitory Activity",

abstract = "A new flavone glycoside, lumnitzerone (1), was isolated from leaves of Lumnitzera littorea, together with 9 known flavonoids. Their structures were elucidated by spectroscopic (one-dimensional, two-dimensional nuclear magnetic resonance) and high-resolution mass spectrometry analysis, and comparison with literature data. Extracts and all isolated compounds were evaluated for α-glucosidase inhibitory activity; all the extracts and most of the isolated compounds exhibited better activities than the positive control acarbose.",

keywords = "flavonoid, glucosidase inhibitor, mangrove, flavonoids, alpha-glucosidase activity",

author = "Nguyen, {Thuy L.T.} and Pham, {Thuy T.} and Bui, {Tung T.} and Huynh, {Loc T.} and Truong, {Dang T.T.} and Le, {Ngoc L.} and Nguyen, {Duc X.} and Le, {Dung L.} and Hansen, {Poul Erik} and Nguyen, {K. P. Phung}",

year = "2019",

month = may,

day = "1",

doi = "10.1177/1934578X19851361",

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journal = "Natural Product Communications",

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A New Flavone Glycoside from Lumnitzera littorea with in vitro α-Glucosidase Inhibitory Activity. / Nguyen, Thuy L.T.; Pham, Thuy T.; Bui, Tung T.; Huynh, Loc T.; Truong, Dang T.T.; Le, Ngoc L.; Nguyen, Duc X. ; Le, Dung L.; Hansen, Poul Erik; Nguyen, K. P. Phung.

I: Natural Product Communications, Bind 14, Nr. 6, 01.05.2019, s. 1-5.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

TY - JOUR

T1 - A New Flavone Glycoside from Lumnitzera littorea with in vitro α-Glucosidase Inhibitory Activity

AU - Nguyen, Thuy L.T.

AU - Pham, Thuy T.

AU - Bui, Tung T.

AU - Huynh, Loc T.

AU - Truong, Dang T.T.

AU - Le, Ngoc L.

AU - Nguyen, Duc X.

AU - Le, Dung L.

AU - Hansen, Poul Erik

AU - Nguyen, K. P. Phung

PY - 2019/5/1

Y1 - 2019/5/1

N2 - A new flavone glycoside, lumnitzerone (1), was isolated from leaves of Lumnitzera littorea, together with 9 known flavonoids. Their structures were elucidated by spectroscopic (one-dimensional, two-dimensional nuclear magnetic resonance) and high-resolution mass spectrometry analysis, and comparison with literature data. Extracts and all isolated compounds were evaluated for α-glucosidase inhibitory activity; all the extracts and most of the isolated compounds exhibited better activities than the positive control acarbose.

AB - A new flavone glycoside, lumnitzerone (1), was isolated from leaves of Lumnitzera littorea, together with 9 known flavonoids. Their structures were elucidated by spectroscopic (one-dimensional, two-dimensional nuclear magnetic resonance) and high-resolution mass spectrometry analysis, and comparison with literature data. Extracts and all isolated compounds were evaluated for α-glucosidase inhibitory activity; all the extracts and most of the isolated compounds exhibited better activities than the positive control acarbose.

KW - flavonoid

KW - glucosidase inhibitor

KW - mangrove

KW - flavonoids

KW - alpha-glucosidase activity

U2 - 10.1177/1934578X19851361

DO - 10.1177/1934578X19851361

M3 - Journal article

VL - 14

SP - 1

EP - 5

JO - Natural Product Communications

JF - Natural Product Communications

SN - 1934-578X

IS - 6

ER -