A New Flavone Glycoside from Lumnitzera littorea with in vitro α-Glucosidase Inhibitory Activity

Thuy L.T. Nguyen, Thuy T. Pham, Tung T. Bui, Loc T. Huynh, Dang T.T. Truong, Ngoc L. Le, Duc X. Nguyen, Dung L. Le, Poul Erik Hansen, K. P. Phung Nguyen

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Abstract

A new flavone glycoside, lumnitzerone (1), was isolated from leaves of Lumnitzera littorea, together with 9 known flavonoids. Their structures were elucidated by spectroscopic (one-dimensional, two-dimensional nuclear magnetic resonance) and high-resolution mass spectrometry analysis, and comparison with literature data. Extracts and all isolated compounds were evaluated for α-glucosidase inhibitory activity; all the extracts and most of the isolated compounds exhibited better activities than the positive control acarbose.
OriginalsprogEngelsk
TidsskriftNatural Product Communications
Vol/bind14
Udgave nummer6
Sider (fra-til)1-5
Antal sider5
ISSN1934-578X
DOI
StatusUdgivet - 1 maj 2019

Emneord

  • flavonoid
  • glucosidase inhibitor
  • mangrove

Citer dette

Nguyen, T. L. T., Pham, T. T., Bui, T. T., Huynh, L. T., Truong, D. T. T., Le, N. L., Nguyen, D. X., Le, D. L., Hansen, P. E., & Nguyen, K. P. P. (2019). A New Flavone Glycoside from Lumnitzera littorea with in vitro α-Glucosidase Inhibitory Activity. Natural Product Communications, 14(6), 1-5. https://doi.org/10.1177/1934578X19851361