1951 Influenza Epidemic, England and Wales, Canada, and the United States

Cecile Viboud, Theresa Tam, Douglas Fleming, Mark A. Miller, Lone Simonsen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Influenza poses a continuing public health threat in epidemic and pandemic seasons. The 1951 influenza epidemic (A/H1N1) caused an unusually high death toll in England; in particular, weekly deaths in Liverpool even surpassed those of the 1918 pandemic. We further quantified the death rate of the 1951 epidemic in 3 countries. In England and Canada, we found that excess death rates from pneumonia and influenza and all causes were substantially higher for the 1951 epidemic than for the 1957 and 1968 pandemics (by >50%). The age-specific pattern of deaths in 1951 was consistent with that of other interpandemic seasons; no age shift to younger age groups, reminiscent of pandemics, occurred in the death rate. In contrast to England and Canada, the 1951 epidemic was not particularly severe in the United States. Why this epidemic was so severe in some areas but not others remains unknown and highlights major gaps in our understanding of interpandemic influenza.
OriginalsprogEngelsk
TidsskriftEmerging Infectious Diseases
Vol/bind12
Udgave nummer4
Antal sider8
DOI
StatusUdgivet - 2006
Udgivet eksterntJa

Citer dette

Viboud, Cecile ; Tam, Theresa ; Fleming, Douglas ; Miller, Mark A. ; Simonsen, Lone. / 1951 Influenza Epidemic, England and Wales, Canada, and the United States. I: Emerging Infectious Diseases. 2006 ; Bind 12, Nr. 4.
@article{34a3374cd3d94dc4a5c6696b7b6670b8,
title = "1951 Influenza Epidemic, England and Wales, Canada, and the United States",
abstract = "Influenza poses a continuing public health threat in epidemic and pandemic seasons. The 1951 influenza epidemic (A/H1N1) caused an unusually high death toll in England; in particular, weekly deaths in Liverpool even surpassed those of the 1918 pandemic. We further quantified the death rate of the 1951 epidemic in 3 countries. In England and Canada, we found that excess death rates from pneumonia and influenza and all causes were substantially higher for the 1951 epidemic than for the 1957 and 1968 pandemics (by >50{\%}). The age-specific pattern of deaths in 1951 was consistent with that of other interpandemic seasons; no age shift to younger age groups, reminiscent of pandemics, occurred in the death rate. In contrast to England and Canada, the 1951 epidemic was not particularly severe in the United States. Why this epidemic was so severe in some areas but not others remains unknown and highlights major gaps in our understanding of interpandemic influenza.",
keywords = "influenza, pneumonia, excess mortality, pandemic, epidemic, United States, England, Canada, Viral strains, immunity, transmissibility, research",
author = "Cecile Viboud and Theresa Tam and Douglas Fleming and Miller, {Mark A.} and Lone Simonsen",
year = "2006",
doi = "10.3201/eid1204.050695",
language = "English",
volume = "12",
journal = "Emerging Infectious Diseases",
number = "4",

}

1951 Influenza Epidemic, England and Wales, Canada, and the United States. / Viboud, Cecile; Tam, Theresa; Fleming, Douglas; Miller, Mark A.; Simonsen, Lone.

I: Emerging Infectious Diseases, Bind 12, Nr. 4, 2006.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - 1951 Influenza Epidemic, England and Wales, Canada, and the United States

AU - Viboud, Cecile

AU - Tam, Theresa

AU - Fleming, Douglas

AU - Miller, Mark A.

AU - Simonsen, Lone

PY - 2006

Y1 - 2006

N2 - Influenza poses a continuing public health threat in epidemic and pandemic seasons. The 1951 influenza epidemic (A/H1N1) caused an unusually high death toll in England; in particular, weekly deaths in Liverpool even surpassed those of the 1918 pandemic. We further quantified the death rate of the 1951 epidemic in 3 countries. In England and Canada, we found that excess death rates from pneumonia and influenza and all causes were substantially higher for the 1951 epidemic than for the 1957 and 1968 pandemics (by >50%). The age-specific pattern of deaths in 1951 was consistent with that of other interpandemic seasons; no age shift to younger age groups, reminiscent of pandemics, occurred in the death rate. In contrast to England and Canada, the 1951 epidemic was not particularly severe in the United States. Why this epidemic was so severe in some areas but not others remains unknown and highlights major gaps in our understanding of interpandemic influenza.

AB - Influenza poses a continuing public health threat in epidemic and pandemic seasons. The 1951 influenza epidemic (A/H1N1) caused an unusually high death toll in England; in particular, weekly deaths in Liverpool even surpassed those of the 1918 pandemic. We further quantified the death rate of the 1951 epidemic in 3 countries. In England and Canada, we found that excess death rates from pneumonia and influenza and all causes were substantially higher for the 1951 epidemic than for the 1957 and 1968 pandemics (by >50%). The age-specific pattern of deaths in 1951 was consistent with that of other interpandemic seasons; no age shift to younger age groups, reminiscent of pandemics, occurred in the death rate. In contrast to England and Canada, the 1951 epidemic was not particularly severe in the United States. Why this epidemic was so severe in some areas but not others remains unknown and highlights major gaps in our understanding of interpandemic influenza.

KW - influenza

KW - pneumonia

KW - excess mortality

KW - pandemic

KW - epidemic

KW - United States

KW - England

KW - Canada

KW - Viral strains

KW - immunity

KW - transmissibility

KW - research

U2 - 10.3201/eid1204.050695

DO - 10.3201/eid1204.050695

M3 - Journal article

VL - 12

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 4

ER -